The guanine nucleotide-binding switch in three dimensions
about
The pseudo GTPase CENP-M drives human kinetochore assemblyStructural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexinMutations in the cilia gene ARL13B lead to the classical form of Joubert syndromeThe GTPase-activating protein Rap1GAP uses a catalytic asparagineThe complex of Arl2-GTP and PDE delta: from structure to functionThe guanine cap of human guanylate-binding protein 1 is responsible for dimerization and self-activation of GTP hydrolysisStructural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome traffickingStructural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranesStructural basis for the reversible activation of a Rho protein by the bacterial toxin SopE.Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligaseHuman OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteinsHigh resolution crystal structures of human Rab4a in its active and inactive conformationsStructural basis of Rab5-Rabaptin5 interaction in endocytosisInsight into the mode of action of the LRRK2 Y1699C pathogenic mutantThe intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.Structure and function of the intracellular region of the plexin-b1 transmembrane receptorStructural basis of family-wide Rab GTPase recognition by rabenosyn-5Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch IIStructural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3Large nucleotide-dependent conformational change in Rab28The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residuesStructural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrAExo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication.Mechanism of the spatio-temporal regulation of Ras and Rap1.Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate bindingRational design of small molecule inhibitors targeting RhoA subfamily Rho GTPasesInsights into the classification of small GTPasesThe Ras protein superfamily: evolutionary tree and role of conserved amino acidsPhosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulenceThe activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondiiElongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-TuATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwindingIdentification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulationInsights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domainThe DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activationAn internal GAP domain negatively regulates presynaptic dynamin in vivo: a two-step model for dynamin function
P2860
Q21128755-8E857070-220D-469D-B1DE-5F7494C591BBQ21128780-498EC532-C9E4-497C-8B5D-DEAA9B250ECAQ21710711-25DD0C87-61B6-4594-A056-7E0C5A617CE5Q24293002-D1E095C9-91CD-4C92-9D9C-910B6AD72471Q24295264-3D082C35-42D4-4D3A-91F1-2D59031644E2Q24296252-EA6C585A-89B6-4F90-B96C-E629BE0B8230Q24298355-EBCD791B-C7E3-4666-B6C2-D061BD48B0A3Q24298929-2D298EA3-089D-4194-9FF0-0C0223E1DA31Q24299379-4128F97F-CB2A-4D71-BF79-59685064D17BQ24300730-C4C5AA0D-2482-42AC-AC85-1F260C53DC74Q24300948-B0F5033F-40D9-487B-A29B-5D95FDE89F73Q24302431-B8C9CCAE-5263-4B3C-9592-9A5ABA751868Q24302876-CFCC9D41-D247-4646-B539-AB9F08CA50EDQ24304419-95C9A668-8305-4366-B04D-5140AB10EE4FQ24306788-FD552CFB-E87A-4796-A0FA-980DE9183537Q24307668-3391DBCC-3C37-41D4-85E6-C72A42AF3920Q24309186-4C3F75CE-D28F-4228-BC1B-E1D23D08A33EQ24309272-73536CB7-A82C-4E82-A1D0-BA790C8D2CA6Q24309371-DFABAF1A-3530-4E21-AE40-F1AD3628AE1DQ24313621-3886FD6B-E1AE-4382-BCAA-D18C1633D8E2Q24315798-0EDDBEE5-E608-41E5-B946-C2343C9E97F3Q24316429-6CF6A612-2AF5-4E6A-984E-3D2ECEF1C9A9Q24318951-D0DB0305-A38A-4735-A142-4A11C4247096Q24321974-CD959672-F911-4E7E-98B1-0A952BA44E0FQ24529568-0C2A011F-1BBC-4133-AF24-8992CE75CB7CQ24538810-5E429BA2-DE5A-4595-BE06-0B632B8CCD5BQ24545607-DEF11317-F5A9-4641-8E2D-EA3F4D2C58BAQ24550737-74F1FB18-8285-4C15-B3A6-500DE4998AB8Q24597996-37078F07-2169-4112-842B-6766349B9BBBQ24599535-EF93C6A4-7646-4C78-A647-E55CA66A4D65Q24603374-7A70A4B4-665A-42C9-B80A-C390D75DAFCCQ24617053-0788E743-9C5E-48D1-AC3E-DDA0DACFEEFFQ24617222-728F419B-28D3-4539-A978-64441CC9E68EQ24633187-1B2CDBD4-FA66-4ABF-A817-948473E1EB59Q24646651-807A1BCA-FC30-4F55-94A0-404011729294Q24650032-382E15B5-7F74-4C72-940C-6C3729CDCC0DQ24656578-CF0D6989-A8DB-4C18-8711-9B9EA53758C4Q24658016-F0EA49B5-A3B9-4D81-B63C-B940E09E2187Q24675414-80C73550-04A8-44A4-A4DE-08D3762D3C3CQ24678397-957B217B-784E-44CF-B61F-74910C3A01F5
P2860
The guanine nucleotide-binding switch in three dimensions
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The guanine nucleotide-binding switch in three dimensions
@ast
The guanine nucleotide-binding switch in three dimensions
@en
The guanine nucleotide-binding switch in three dimensions
@nl
type
label
The guanine nucleotide-binding switch in three dimensions
@ast
The guanine nucleotide-binding switch in three dimensions
@en
The guanine nucleotide-binding switch in three dimensions
@nl
prefLabel
The guanine nucleotide-binding switch in three dimensions
@ast
The guanine nucleotide-binding switch in three dimensions
@en
The guanine nucleotide-binding switch in three dimensions
@nl
P3181
P356
P1433
P1476
The guanine nucleotide-binding switch in three dimensions
@en
P2093
A Wittinghofer
I R Vetter
P304
P3181
P356
10.1126/SCIENCE.1062023
P407
P577
2001-11-09T00:00:00Z