Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis.
about
sameAs
The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expressionInsertional mutagenesis reveals progression genes and checkpoints in MYC/Runx2 lymphomasDetecting statistically significant common insertion sites in retroviral insertional mutagenesis screensThe c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor geneJDP2 (Jun Dimerization Protein 2)-deficient mouse embryonic fibroblasts are resistant to replicative senescenceThe ubiquitously expressed bZIP inhibitor, JDP2, suppresses the transcription of its homologue immediate early gene counterpart, ATF3Involvement of Jun dimerization protein 2 (JDP2) in the maintenance of Epstein-Barr virus latencyHematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integrationActivation of alternative Jdp2 promoters and functional protein isoforms in T-cell lymphomas by retroviral insertion mutagenesisFgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomasThe AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in miceTRE-dependent transcription activation by JDP2-CHOP10 associationRas inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosisSuppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2JDP2 suppresses adipocyte differentiation by regulating histone acetylationRegulation of histone acetylation and nucleosome assembly by transcription factor JDP2The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesisPhosphorylation of JDP2 on threonine-148 by the c-Jun N-terminal kinase targets it for proteosomal degradationEffect of Xpcl1 activation and p27(Kip1) loss on gene expression in murine lymphomaMicroRNAs and genomic instability.Orthologous microRNA genes are located in cancer-associated genomic regions in human and mouseA mechanism misregulating p27 in tumors discovered in a functional genomic screen.Pvt1-encoded microRNAs in oncogenesis.Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate.Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypesRadiation leukemia virus common integration at the Kis2 locus: simultaneous overexpression of a novel noncoding RNA and of the proximal Phf6 geneAn Integrated Genetic-Genomic Approach for the Identification of Novel Cancer Loci in Mice Sensitized to c-Myc-Induced Apoptosis.Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice.Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1Retroviral activation of the mir-106a microRNA cistron in T lymphoma.When reverse genetics meets physiology: the use of site-specific recombinases in mice.RTCGD: retroviral tagged cancer gene database.Cancer gene discovery in mouse and man.Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.Retroviruses hijack chromatin loops to drive oncogene expression and highlight the chromatin architecture around proto-oncogenic loci.Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer GenomicsDnmt3a Is a Haploinsufficient Tumor Suppressor in CD8+ Peripheral T Cell Lymphoma.The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models.Retroviral insertional mutagenesis: past, present and future.Host JDP2 expression in the bone marrow contributes to metastatic spread
P2860
Q24536056-2203B8EA-E3CB-4385-9F47-AD5DFAE6918EQ24657196-1D06F251-EA1B-4862-9F01-B5B2A74ADB47Q27339599-9AB857D6-8B75-44CE-81B0-3E82DC25211DQ28185692-E7247EFD-D02B-417B-81AD-4C0C31D1F138Q28235883-708714A1-BFB7-4C54-94F3-1228A2CB779CQ28235904-2F8823A7-F573-4967-AE5E-4697D45AC06AQ28236382-B47057B0-86D0-4EAC-B7BA-294C737CAAACQ28242708-59F5A5E5-CC0A-45AF-A674-613123906DBAQ28247627-E57F570B-FB5E-4BAA-B8C9-47B1221FC743Q28267846-9E9F21F6-A9E8-45B4-B40C-7C038ED0BFF7Q28275462-B55E9BAF-A7A9-422B-A9B0-4780615672A5Q28279375-4ACA832A-3D17-4B1B-ADB2-8F8465E9C393Q28287799-26F79E31-4F6C-42C3-A48B-812820438930Q28292002-FE5455A4-880C-4EF6-8777-055E512BBFD7Q28299658-891281BE-5D97-46D0-98CA-B75E4CB53FBEQ28300507-ADC5896D-CED3-4811-A53C-D5F2C6714869Q28305297-0397A3B6-0035-4752-9CE8-5FCFF16583DBQ28308199-5DAEAF61-3927-4F2C-A181-767C6B771DA2Q28742014-5F982A6D-C32C-4642-BF18-2A7160D2BE20Q31078551-15DD92B3-766E-4ECB-A7D9-DD0CC67786D2Q33305346-FCCCDF0C-0C4A-47EF-939F-987F8C38DDB1Q33309464-F8DED577-9B91-4137-AD8F-D764CFCB6628Q33345075-AB7C922B-40FE-4274-A53F-AC43922A3C6DQ33564004-9F2F57D8-D9F0-4810-A88A-EA68CF57C0C7Q33871572-69B3E667-C8C5-476A-A635-979A535E444AQ33930366-B2953922-8966-4B60-8837-1EFB6793190BQ34171480-922FFBD7-854B-484A-A601-1A6BDBE6BCE1Q34549869-6B55AE5E-6B57-47E3-A1C5-3E7629110741Q34572977-6AC95225-2F98-470D-87DD-5C80D2F76919Q34620231-C5A70A26-12FC-45D6-A58F-1E6E11265404Q34922275-7ED80BAE-F6D9-45E9-A878-23F4A47DF802Q34923778-3A80634C-EF9D-4BE5-8B71-338180A711EFQ34962407-AE0BC9CE-A7F9-4AED-939A-F91C62A5DC41Q35105746-9A22DBA4-8504-4E5E-AEC9-E79B13102F1CQ35584064-E36F5856-A8C9-4368-8DBA-1DB40DDDD82DQ35994982-D27283D7-C155-4B5D-9533-43C696504B99Q36149906-31ED8625-9E8F-4ADF-89F4-FB75804671FEQ36309953-7B6035AD-28B1-4FD3-9861-DFC1ED33706DQ36318150-2333BA0A-D94A-4066-8EBF-6D2599AB3788Q36545857-727B3216-705A-40F7-AF46-5F9BF5B239CE
P2860
Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Identification of oncogenes co ...... ughput insertion site analysis
@nl
Identification of oncogenes co ...... ghput insertion site analysis.
@ast
Identification of oncogenes co ...... ghput insertion site analysis.
@en
type
label
Identification of oncogenes co ...... ughput insertion site analysis
@nl
Identification of oncogenes co ...... ghput insertion site analysis.
@ast
Identification of oncogenes co ...... ghput insertion site analysis.
@en
prefLabel
Identification of oncogenes co ...... ughput insertion site analysis
@nl
Identification of oncogenes co ...... ghput insertion site analysis.
@ast
Identification of oncogenes co ...... ghput insertion site analysis.
@en
P2093
P2860
P3181
P356
P1476
Identification of oncogenes co ...... ghput insertion site analysis.
@en
P2093
Anton Berns
Bruce E Clurman
Carla P Martins
Erin Randel
Harry C Hwang
Matthew Fero
Yvon Bronkhorst
P2860
P304
11293-11298
P3181
P356
10.1073/PNAS.162356099
P407
P577
2002-07-31T00:00:00Z