The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses - Wikidata - thesis-toulmin - TriplyDB

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

http://www.wikidata.org/entity/Q28240102

about

TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1 Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1 Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1 Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR Spatial regulation of the mTORC1 system in amino acids sensing pathway An emerging role for TOR signaling in mammalian tissue and stem cell physiology Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony mTOR signaling in growth control and disease The TSC1-TSC2 complex: a molecular switchboard controlling cell growth Systems biology: On the cell cycle and its switches A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling Transcriptional regulation of hepatic lipogenesis The molecular basis for load-induced skeletal muscle hypertrophy mTOR-dependent cell survival mechanisms Leucine and mTORC1: a complex relationship Regulation of mTORC1 by PI3K signaling Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR Nutrient-sensing mechanisms across evolution Regulation of mTORC1 by amino acids Nutrient regulation of the mTOR complex 1 signaling pathway Rag proteins regulate amino-acid-induced mTORC1 signalling.A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex Is REDD1 a Metabolic Éminence Grise?The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1 A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks Where is mTOR and what is it doing there?Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo Bidirectional transport of amino acids regulates mTOR and autophagy Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer?Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.TOR and PKA pathways synergize at the level of the Ste11 transcription factor to prevent mating and meiosis in fission yeast.TOR-dependent control of autophagy: biting the hand that feeds

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The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

http://www.wikidata.org/entity/Q28240102

description

2005 nî lūn-bûn

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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2005 թվականի մայիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

The tuberous sclerosis protein ...... and certain cellular stresses

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The tuberous sclerosis protein ...... and certain cellular stresses

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The tuberous sclerosis protein ...... and certain cellular stresses

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type

label

The tuberous sclerosis protein ...... and certain cellular stresses

@ast

The tuberous sclerosis protein ...... and certain cellular stresses

@en

The tuberous sclerosis protein ...... and certain cellular stresses

@nl

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The tuberous sclerosis protein ...... and certain cellular stresses

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The tuberous sclerosis protein ...... and certain cellular stresses

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The tuberous sclerosis protein ...... and certain cellular stresses

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P1433

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P3181

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P1433

Journal of Biological Chemistry

P1476

The tuberous sclerosis protein ...... and certain cellular stresses

@en

P2093

Gareth J Browne

http://www.w3.org/2001/XMLSchema#string

Stephen G Finn

http://www.w3.org/2001/XMLSchema#string

P2860

The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Regulation of TSC2 by 14-3-3 binding

Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K

Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation

Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin

P304

18717-18727

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scholarly article

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1247463

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P356

10.1074/JBC.M414499200

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P433

19

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P478

280

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P50

Christopher G. Proud

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2005-03-16T00:00:00Z

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P698

15772076

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