BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases
about
Highlight: BRCA1 and BRCA2 proteins in breast cancerConstitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.CAS, the human homologue of the yeast chromosome-segregation gene CSE1, in proliferation, apoptosis, and cancer.BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation siteBRCA1 and BRCA2 proteins: roles in health and diseaseRegulation of E2F1 by BRCT domain-containing protein TopBP1BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells.The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular LocationsBARD1 may be renamed ROW1 because it functions mainly as a REPRESSOR OF WUSCHEL1The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutationc-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cellsDisruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein bindingThe second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoterBRCA1 and Oxidative StressPhosphorylated BRCA1 is predominantly located in the nucleus and mitochondriaBARD1 participates with BRCA1 in homology-directed repair of chromosome breaksConstitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells.The functions of breast cancer susceptibility gene 1 (BRCA1) product and its associated proteins.Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation.BRCA1 and BRCA2 mutations and treatment strategies for breast cancer.Emerging roles of BRCA1 alternative splicing.Transcriptional autoregulation by BRCA1.BRCA1 and prostate cancer.Neoplastic transformation of human breast epithelial cells by estrogens and chemical carcinogens.A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells.Characterization of three alternative transcripts of the BRCA1 gene in patients with breast cancer and a family history of breast and/or ovarian cancer who tested negative for pathogenic mutations.A novel E2F-like protein involved in transcriptional activation of cyst wall protein genes in Giardia lamblia.Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteinsPrognosis of treatment response (pathological complete response) in breast cancer.BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9Suppression of BRCA1 sensitizes cells to proteasome inhibitors.Biomarkers and the genetics of early neoplastic lesions.Mitochondrial localization, ELK-1 transcriptional regulation and growth inhibitory functions of BRCA1, BRCA1a, and BRCA1b proteinsThe role of the retinoblastoma/E2F1 tumor suppressor pathway in the lesion recognition step of nucleotide excision repair.Crucial role for early growth response-1 in the transcriptional regulation of miR-20b in breast cancerSystems biology-based identification of crosstalk between E2F transcription factors and the Fanconi anemia pathway.Regulatory landscape and clinical implication of MBD3 in human malignant glioma.BRCA1 16 years later: nuclear import and export processes.Role of protein-protein interactions in the antiapoptotic function of EWS-Fli-1.BRCA1 gene expression in breast cancer: a correlative study between real-time RT-PCR and immunohistochemistry.
P2860
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P2860
BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@ast
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@en
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@nl
type
label
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@ast
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@en
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@nl
prefLabel
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@ast
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@en
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@nl
P2093
P356
P1433
P1476
BRCA1 proteins are transported ...... s and cyclin dependent kinases
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1201252
P407
P577
1997-07-10T00:00:00Z
P5875
P6179
1046060571