Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
about
PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathwayMelanoma: from melanocyte to genetic alterations and clinical optionsDetection of three novel translocation and specific common chromosomal break sites in malignant melanoma by spectral karyotypingThe response of autologous T cells to a human melanoma is dominated by mutated neoantigensLoss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneityGerm line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence.POT1 loss-of-function variants predispose to familial melanomaStructural basis of inhibition of CDK-cyclin complexes by INK4 inhibitorsRequirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C MutationPolymorphisms in the syntaxin 17 gene are not associated with human cutaneous malignant melanomaMutation testing in melanoma families: INK4A, CDK4 and INK4DTowards a Better Understanding of the Molecular Mechanisms Involved in Sunlight-Induced MelanomaUpdate in genetic susceptibility in melanomaTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsPathways and therapeutic targets in melanomaMelanoma: from mutations to medicineLoss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines.cdk6 can shorten G(1) phase dependent upon the N-terminal INK4 interaction domainInactivation of p16/CDKN2 and p15/MTS2 is associated with prognosis and response to chemotherapy in ovarian cancerCooperation of DLC1 and CDK6 affects breast cancer clinical outcomeFamilial malignant melanoma - overviewIndole-3-carbinol inhibits nasopharyngeal carcinoma growth through cell cycle arrest in vivo and in vitroGenetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell numberA Comprehensive Review of Pediatric Tumors and Associated Cancer Predisposition Syndromes.Hereditary genodermatoses with cancer predispositionMapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition.Realizing the promise of cancer predisposition genes.Prevalence of variations in melanoma susceptibility genes among Slovenian melanoma families.Mutation screening of CHD5 in melanoma-prone families linked to 1p36 revealed no deleterious coding or splice site changes.Insights into cancer from transgenic mouse models.Genomic analysis and clinical management of adolescent cutaneous melanoma.Melanoma genetics and the development of rational therapeutics.Rare missense variants in POT1 predispose to familial cutaneous malignant melanomaThe genetics of hereditary melanoma and nevi. 1998 update.Structural basis for the modulation of CDK-dependent/independent activity of cyclin D1.A new functional classification of tumor-suppressing genes and its therapeutic implications.Localization of a novel melanoma susceptibility locus to 1p22Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors.Invasive melanoma in Cdk4-targeted mice.MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations
P2860
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P2860
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@ast
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@en
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@nl
type
label
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@ast
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@en
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@nl
prefLabel
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@ast
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@en
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@nl
P2093
P356
P1433
P1476
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
@en
P2093
A M Goldstein
G J Walker
M A Tucker
N C Dracopoli
P2888
P356
10.1038/NG0196-97
P407
P577
1996-01-01T00:00:00Z
P6179
1049406648