AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
about
Inhibition of calcineurin phosphatase activity by a calcineurin B homologous proteinDiscs large (Dlg1) complexes in lymphocyte activationCHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cellsAKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complexDeletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cellsMolecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling UnitsA conserved family of calcineurin regulators.Localization of the A kinase anchoring protein AKAP79 in the human hippocampusAssociation of protein kinase A with AKAP150 facilitates pepsinogen secretion from gastric chief cellsNFAT proteins: key regulators of T-cell development and functionNetworking with AKAPs: context-dependent regulation of anchored enzymesTargeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophyA critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptorsMutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.AKAP79 and the evolution of the AKAP model.A calcineurin/AKAP complex is required for NMDA receptor-dependent long-term depression.Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy.A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a.Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivoCarvedilol reverses cardiac insufficiency in AKAP5 knockout mice by normalizing the activities of calcineurin and CaMKII.Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatusAKAPs (A-kinase anchoring proteins) and molecules that compose their G-protein-coupled receptor signalling complexes.Imaging kinase--AKAP79--phosphatase scaffold complexes at the plasma membrane in living cells using FRET microscopy.Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin.Mapping the protein phosphatase-2B anchoring site on AKAP79. Binding and inhibition of phosphatase activity are mediated by residues 315-360.Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway.Opposing actions of inositol 1,4,5-trisphosphate and ryanodine receptors on nuclear factor of activated T-cells regulation in smooth muscle.African swine fever virus protein A238L interacts with the cellular phosphatase calcineurin via a binding domain similar to that of NFAT.The catalytically active domain in the A subunit of calcineurin.A conserved calcineurin-binding motif in human T lymphotropic virus type 1 p12I functions to modulate nuclear factor of activated T cell activation.Synergism between the calmodulin-binding and autoinhibitory domains on calcineurin is essential for the induction of their phosphatase activity.G protein-coupled estrogen receptor 1 (GPER1)/GPR30 increases ERK1/2 activity through PDZ motif-dependent and -independent mechanisms.Serine/Threonine phosphatases: classification, roles and pharmacological regulation.
P2860
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P2860
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@ast
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@en
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@nl
type
label
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@ast
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@en
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@nl
prefLabel
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@ast
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@en
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@nl
P2093
P2860
P3181
P356
P1476
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.273.42.27412
P407
P577
1998-10-16T00:00:00Z