The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity
about
Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell TypesRadiotherapy combination opportunities leveraging immunity for the next oncology practiceChimeric Antigen Receptor-Modified T Cells for Solid Tumors: Challenges and ProspectsThe Next Hurdle in Cancer Immunotherapy: Overcoming the Non-T-Cell-Inflamed Tumor MicroenvironmentCombining radiotherapy with sunitinib: lessons (to be) learnedThe effect of radiation on the immune response to cancersInnate and adaptive immune cells in the tumor microenvironmentThe STING pathway and the T cell-inflamed tumor microenvironmentTargeting and utilizing primary tumors as live vaccines: changing strategiesHost immune response to infection and cancer: unexpected commonalitiesCombining radiotherapy and cancer immunotherapy: a paradigm shiftRadiotherapy and the tumor stroma: the importance of dose and fractionationType I interferon response and innate immune sensing of cancerDecoding the complexity of type I interferon to treat persistent viral infectionsImmunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor MicroenvironmentThe Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor EfficacyImmunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?Molecular Pathways: Targeting the Stimulator of Interferon Genes (STING) in the Immunotherapy of CancerThe abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevantHarnessing the Power of Onco-Immunotherapy with Checkpoint InhibitorsNew perspectives on type I IFNs in cancerHigh efficiency cell-specific targeting of cytokine activityEnhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumorsRational combinations of immunotherapeutics that target discrete pathways.Randomized controlled phase I/II study to investigate immune stimulatory effects by low dose radiotherapy in primarily operable pancreatic cancerComplement-dependent modulation of antitumor immunity following radiation therapy.Treatment of 4T1 metastatic breast cancer with combined hypofractionated irradiation and autologous T-cell infusion.Radical irradiation of extracranial oligometastases.Considerations for combined immune checkpoint modulation and radiation treatment.Host STAT2/type I interferon axis controls tumor growth.DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.Combinations of immunotherapy and radiation in cancer therapy.STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells.Stereotactic Radiation Therapy Augments Antigen-Specific PD-1-Mediated Antitumor Immune Responses via Cross-Presentation of Tumor AntigenSoluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathwaysCombining α-Radioimmunotherapy and Adoptive T Cell Therapy to Potentiate Tumor Destruction.Gene therapy for cancer: present status and future perspectiveTargeting the inhibitory receptor CTLA-4 on T cells increased abscopal effects in murine mesothelioma model.TGFβ Is a Master Regulator of Radiation Therapy-Induced Antitumor ImmunityAblative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions
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P2860
The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@ast
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@en
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@nl
type
label
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@ast
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@en
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@nl
prefLabel
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@ast
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@en
The efficacy of radiotherapy r ...... t innate and adaptive immunity
@nl
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The efficacy of radiotherapy r ...... t innate and adaptive immunity
@en
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Byron C Burnette
Lukasz Chlewicki
Nikolai N Khodarev
Sogyong L Auh
Youjin Lee
P2860
P304
P3181
P356
10.1158/0008-5472.CAN-10-2820
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P577
2011-04-01T00:00:00Z