Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
about
Mitochondria Initiate and Regulate SarcopeniaMutations that Allow SIR2 Orthologs to Function in a NAD+-Depleted Environment.Meat and Nicotinamide: A Causal Role in Human Evolution, History, and Demographics.Meat Intake and the Dose of Vitamin B3 - Nicotinamide: Cause of the Causes of Disease Transitions, Health Divides, and Health Futures?Cardioprotective Effects of SIRT6 in a Mouse Model of Transverse Aortic Constriction-Induced Heart Failure.Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapyPhysiological links of circadian clock and biological clock of aging.A conserved NAD+ binding pocket that regulates protein-protein interactions during aging.Impact of Yoga and Meditation on Cellular Aging in Apparently Healthy Individuals: A Prospective, Open-Label Single-Arm Exploratory Study.Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma.Growth factor, energy and nutrient sensing signalling pathways in metabolic ageing.Chromatin Changes Associated with Neuronal Maintenance and Their Pharmacological Application.Mediterranean diet and inflammaging within the hormesis paradigm.CD38 positively regulates postnatal development of astrocytes cell-autonomously and oligodendrocytes non-cell-autonomously.Melatonin reverses H2 O2 -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB.Key proteins and pathways that regulate lifespan.Sirtuins, a promising target in slowing down the ageing process.SIRT6: Novel Mechanisms and Links to Aging and Disease.Could Sirtuin Activities Modify ALS Onset and Progression?Mitophagy in neurodegeneration and aging.Mitophagy Transcriptome: Mechanistic Insights into Polyphenol-Mediated Mitophagy.Aging and Caloric Restriction Research: A Biological Perspective With Translational Potential.Identification of a Tissue-Restricted Isoform of SIRT1 Defines a Regulatory Domain that Encodes Specificity.Aging, Metabolism, and Cancer Development: from Peto's Paradox to the Warburg Effect.Resveratrol therapeutics combines both antimicrobial and immunomodulatory properties against respiratory infection by nontypeable Haemophilus influenzae.Regulation of Sirtuin-Mediated Protein Deacetylation by Cardioprotective Phytochemicals.Metabolic programming of the epigenome: host and gut microbial metabolite interactions with host chromatin.Resveratrol for Easing Status Epilepticus Induced Brain Injury, Inflammation, Epileptogenesis, and Cognitive and Memory Dysfunction-Are We There Yet?The landscape of transcription errors in eukaryotic cells.Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study.SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation.Mitochondrial matrix pH as a decisive factor in neurometabolic imaging.Neuronal SIRT1 (Silent Information Regulator 2 Homologue 1) Regulates Glycolysis and Mediates Resveratrol-Induced Ischemic Tolerance.SIRT2 Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy.Metabolic pathways at the crossroads of diabetes and inborn errors.Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors.Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT1 activity and antioxidant gene expression in mouse cells.Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™).NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.Breaking the Ceiling of Human Maximal Lifespan.
P2860
Q29248515-AF466215-D1C3-4652-8447-2A357C0DD1BBQ33609107-E245FE0C-7C50-4501-98B3-8A38B1CB5AAFQ33637828-031333CC-FF85-468F-8357-07EE203BC900Q33642585-F8BAB7ED-7CBC-4724-A337-BEBC4FA80B14Q33789997-3863D831-53ED-47E9-B8C6-E569E407ACBEQ33791807-8C240531-761B-4422-9175-3849FDE2E54EQ33874957-3DF127EF-E987-45AC-B6F2-DA2A328FD5C4Q36321255-177C5294-9FDB-458A-B10F-27405F60B240Q37612062-E0D92EB5-CED6-4F87-8E73-3E3C16919E29Q38600194-5D388EB1-1388-43FE-BFF9-F347055289CEQ38631149-E28669CA-FB90-4370-98B6-5F8E06917130Q38676090-38FA7FE7-6152-4EC5-BD6A-6C7120298804Q38736064-DBEF8B1D-DB64-44C5-A365-DD9663CBD215Q38906787-20612757-E927-4EB3-85BF-7F68E3177B72Q38906794-A31E6371-A6DA-4EE7-975B-08CF2DCA84DEQ38926261-0292CD93-339D-4EDC-9B27-3FA778B025DDQ38930264-C6F4A389-4DCA-43B6-9416-0EBF72D50247Q39005741-CDA13C7C-D405-4380-AA59-8D9535243048Q39036105-FFEA4BA0-4161-4484-9496-6D28CDE8D0C7Q39149860-1B7C44F1-1F56-4192-B5CF-7701FE62D822Q39381679-B30F5A45-68C9-4DE5-9203-F46E35EA5346Q39397591-E81E0EA0-62AB-4BA6-A890-94E83D4F27D3Q41264744-E27D876A-4A48-4A97-84A9-E9EF24066C9BQ42364240-BB691025-BB9B-4AB8-99A2-B040ACE739E8Q42379026-780B0191-53A3-4CD4-A430-A2F2C6C2B583Q45827486-B11CDBB5-63FC-4334-93D8-8D7D07EEE811Q46305658-02E0FCC6-A2CB-4F57-AC9A-3DBAAA9E338EQ46550304-08DB315F-6BEF-45A8-938E-4AD6AE97A5E2Q46955343-B326DAFF-27B3-4879-AE89-BA833BC252CFQ47262257-5692BD4D-3E0C-4801-860F-5F5CB71E3E4AQ47265256-4413A335-3BE5-4498-9A36-70E62F506E02Q47308551-2FF9CA16-898E-4D5F-BC83-BA3B196A3B00Q47669174-F4BD9B43-25DD-4CDF-A130-29CB59619EC9Q47744644-A2BA498B-810A-46A9-A018-842861B0EA5FQ47927670-29AC269F-3A68-4B1C-A61E-F22560D864C9Q48012312-274B006F-F1DF-4041-965F-0A31079442D4Q48231703-4806C051-E0BD-4293-8145-2DD365C8635EQ49606294-CEE2C28E-5E4D-4B17-BB3E-7C2958DD2B0CQ50063845-15863B45-927F-4B55-A462-8FB38DB04FB6Q50092768-07034A10-A38A-4F09-A30A-F6C39370975F
P2860
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
description
2016 nî lūn-bûn
@nan
2016 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@ast
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@en
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@nl
type
label
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@ast
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@en
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@nl
prefLabel
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@ast
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@en
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@nl
P2860
P356
P1476
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds
@en
P2093
David A Sinclair
Michael S Bonkowski
P2860
P2888
P304
P356
10.1038/NRM.2016.93
P407
P577
2016-11-01T00:00:00Z
P6179
1038682840