Functional cross-talk between ras and rho pathways: a Ras-specific GTPase-activating protein (p120RasGAP) competitively inhibits the RhoGAP activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine finger
about
Epidermal growth factor activates the Rho GTPase-activating protein (GAP) Deleted in Liver Cancer 1 via focal adhesion kinase and protein phosphatase 2AA WXW motif is required for the anticancer activity of the TAT-RasGAP317-326 peptideDeciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1.The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment.In vitro studies in a myelogenous leukemia cell line suggest an organized binding of geranylgeranyl diphosphate synthase inhibitorsThe anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration.Targeting protein geranylgeranylation slows tumor development in a murine model of prostate cancer metastasis.Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.
P2860
Q28387833-9CAE1741-AF16-4758-B1EB-E78AEE142E70Q28393795-B8D80BD3-CABA-44BB-8AAF-15A4B8F02C57Q30276221-0392F6C2-918A-468A-A63B-E1365360CB20Q35205434-37EC629A-C824-4F41-9433-A7C80C5AC76BQ36147572-5229F484-B88B-4334-AAA1-47CAB5523F77Q38878009-CEA99654-6A37-49BD-A8EF-1E8DADDE453BQ42103022-998FE976-857F-4109-81E2-4EA3D2E20B41Q47138834-C4875072-941E-49DE-9ED6-A9139DA325C5Q47428473-57DAB8AE-14AC-4210-A993-5ED947FBE18B
P2860
Functional cross-talk between ras and rho pathways: a Ras-specific GTPase-activating protein (p120RasGAP) competitively inhibits the RhoGAP activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine finger
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2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Functional cross-talk between ...... the catalytic arginine finger
@ast
Functional cross-talk between ...... the catalytic arginine finger
@en
Functional cross-talk between ...... the catalytic arginine finger
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type
label
Functional cross-talk between ...... the catalytic arginine finger
@ast
Functional cross-talk between ...... the catalytic arginine finger
@en
Functional cross-talk between ...... the catalytic arginine finger
@nl
prefLabel
Functional cross-talk between ...... the catalytic arginine finger
@ast
Functional cross-talk between ...... the catalytic arginine finger
@en
Functional cross-talk between ...... the catalytic arginine finger
@nl
P2093
P2860
P3181
P356
P1476
Functional cross-talk between ...... the catalytic arginine finger
@en
P2093
Aziz R Gauhar
Claus Kordes
Dieter Häussinger
Ehsan Amin
Eyad K Fansa
Ion C Cirstea
Katja T Koessmeier
Mohamed S Taha
Mohammad R Ahmadian
Monilola A Olayioye
P2860
P304
P3181
P356
10.1074/JBC.M113.527655
P407
P577
2014-03-07T00:00:00Z