Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1
about
Regulation of TOR by small GTPasesSpatial regulation of the mTORC1 system in amino acids sensing pathwayMAPK-Activated Protein Kinases (MKs): Novel Insights and ChallengesMultifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscleA genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylationPDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascadeRegulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networksThe extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphologyComparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAKPhysiological roles of mitogen-activated-protein-kinase-activated p38-regulated/activated protein kinaseHomology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5).Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.Targeting protein prenylation for cancer therapyRecent progress in the study of the Rheb family GTPases.Autophagy, Warburg, and Warburg reverse effects in human cancer.The p38β mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the α-G helix and MAPK insert.Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomicsPRAK interacts with DJ-1 and prevents oxidative stress-induced cell death.Direct Interaction between Ras Homolog Enriched in Brain and FK506 Binding Protein 38 in Cashmere Goat Fetal Fibroblast Cells.Evolving Lessons on the Complex Role of AMPK in Normal Physiology and Cancer.Role of p38 mitogen-activated protein kinase in vascular endothelial aging: interaction with Arginase-II and S6K1 signaling pathwayPhosphorylation of Raptor by p38beta participates in arsenite-induced mammalian target of rapamycin complex 1 (mTORC1) activation.Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.mTORC2 is required for rit-mediated oxidative stress resistance.A novel cardioprotective p38-MAPK/mTOR pathway.Cross-Phosphorylation and Interaction between Src/FAK and MAPKAP5/PRAK in Early Focal Adhesions Controls Cell MotilityAMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts.Tuberous Sclerosis Complex Protein 2-Independent Activation of mTORC1 by Human Cytomegalovirus pUL38.Rheb phosphorylation is involved in p38-regulated/activated protein kinase-mediated tumor suppression in liver cancer.mTORC1 signaling and regulation of pancreatic β-cell mass.Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade.Phosphatase control of 4E-BP1 phosphorylation state is central for glycolytic regulation of retinal protein synthesis.Regulation and function of mTOR signalling in T cell fate decisions.The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer's disease pathogenesisMetabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex.p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin14-3-3 proteins regulate Tctp-Rheb interaction for organ growth in Drosophila.Ras and rheb signaling in survival and cell deathFas-associated protein with death domain (FADD) regulates autophagy through promoting the expression of Ras homolog enriched in brain (Rheb) in human breast adenocarcinoma cellsMetformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1.
P2860
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P2860
Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1
description
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im März 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/03/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/03/01)
@nl
наукова стаття, опублікована в березні 2011
@uk
مقالة علمية (نشرت في مارس 2011)
@ar
name
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@ast
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@en
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@nl
type
label
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@ast
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@en
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@nl
prefLabel
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@ast
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@en
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@nl
P2093
P2860
P921
P3181
P356
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P1476
Inactivation of Rheb by PRAK-m ...... -induced suppression of mTORC1
@en
P2093
Hongbing Zhang
Jiahuai Han
Kun-Liang Guan
Meng-Qiu Dong
Peiqing Sun
Sheng-Cai Lin
Xiao-Nan Wu
P2860
P2888
P304
P3181
P356
10.1038/NCB2168
P577
2011-03-01T00:00:00Z
P5875
P6179
1040222650