Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
about
DNA triplet repeat expansion and mismatch repairGeneration and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell modelsMutLα heterodimers modify the molecular phenotype of Friedreich ataxia.Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approachesBase excision repair of chemotherapeutically-induced alkylated DNA damage predominantly causes contractions of expanded GAA repeats associated with Friedreich's ataxia.Repeat instability during DNA repair: Insights from model systemsThe Repeat Expansion Diseases: The dark side of DNA repair.Mutsβ generates both expansions and contractions in a mouse model of the Fragile X-associated disordersMature microsatellites: mechanisms underlying dinucleotide microsatellite mutational biases in human cells.Crosstalk between MSH2-MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair.Friedreich ataxia: metal dysmetabolism in dorsal root ganglia.The mismatch repair protein MSH2 is rate limiting for repeat expansion in a fragile X premutation mouse model.Animal and cellular models of Friedreich ataxia.The dual nature of mismatch repair as antimutator and mutator: for better or for worse.Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts.Genetic modifiers of Mendelian disease: Huntington's disease and the trinucleotide repeat disorders.GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one.
P2860
Q26996542-7154FC92-4635-4BB4-9A40-7DE57BBECAC8Q28540063-E358C5F0-69AF-4E7D-BDBC-21AEDFE98105Q33817381-79BDAF58-0552-4AA4-91E4-8926451213E6Q35034398-85DFD7F2-9F52-42EF-B67D-F1795B75A6C6Q35137677-463BDA81-0FA8-490A-B232-138668E2520DQ35680075-EA9D2CB6-7756-4F8B-9FB1-B417BBC81EA0Q35909014-C36520C4-4D2C-440B-B1A4-23590A709B1CQ36302118-47024DC8-C169-4D4A-AEB9-5A1F595E78CBQ36642236-95DB6C75-A5F8-4132-A6BB-9AEF6EB973B8Q37201730-28962F38-C110-4C9C-9183-AA12934F0B38Q37485501-EBFACAB9-8314-4674-8C79-D36EF65FADE8Q37632532-A112EF04-C995-43E3-82C3-A2A879B6D83CQ38121944-5D94C3F6-23C4-49B2-AE6F-0BD54C8C98EEQ38246275-682C9E2A-44D5-45BF-A154-14767C083469Q39424134-13AF1C7A-1772-4E50-A1D5-6D100DC7CB75Q49608512-D421F542-B72F-45BB-8D70-5E3F659890F0Q52359109-823B024A-59A3-44BB-8413-7DEE371ADAE2
P2860
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
description
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artikull shkencor
@sq
artículu científicu espublizáu en 2012
@ast
im Januar 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2012
@uk
مقالة علمية (نشرت عام 2012)
@ar
name
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@ast
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@en
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@nl
type
label
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@ast
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@en
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@nl
prefLabel
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@ast
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@en
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@nl
P2093
P2860
P921
P3181
P1433
P1476
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
@en
P2093
Chiranjeevi Sandi
Irene De Biase
Mark A. Pook
Rebecka L. Bourn
Sahar Al-Mahdawi
Sanjay I. Bidichandani
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0047085
P407
P577
2012-01-01T00:00:00Z