Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function
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Constitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration.A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapsesElimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning.Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviorsKalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticityStriatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97/18 mouse model of Huntington diseaseVariations in the stimulus salience of cocaine reward influences drug-associated contextual memoryOptimizing production of Fc-amidated peptides by Chinese hamster ovary cellsAn N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions.A role for kalirin in the response of rat medium spiny neurons to cocaine.Analysis of kalirin-7 knockout mice reveals different effects in female mice.TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function.Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation.Kalirin-7 mediates cocaine-induced AMPA receptor and spine plasticity, enabling incentive sensitization.Modulation of behavior by scaffolding proteins of the post-synaptic density.Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference.Neuronal Rho GEFs in synaptic physiology and behavior.Kalirin, a key player in synapse formation, is implicated in human diseases.Scaffolding proteins of the post-synaptic density contribute to synaptic plasticity by regulating receptor localization and distribution: relevance for neuropsychiatric diseases.Emerging roles of actin cytoskeleton regulating enzymes in drug addiction: actin or reactin'?The glutamatergic aspects of schizophrenia molecular pathophysiology: role of the postsynaptic density, and implications for treatmentEffects of L-3-n-butylphthalide on cognitive dysfunction and NR2B expression in hippocampus of streptozotocin (STZ)-induced diabetic rats.Regulating Rac in the nervous system: molecular function and disease implication of Rac GEFs and GAPs.Alternate promoter usage generates two subpopulations of the neuronal RhoGEF Kalirin-7.The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model.Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease.Kalirin is required for BDNF-TrkB stimulated neurite outgrowth and branching.Structural organization of the nine spectrin repeats of Kalirin.Protective effects of Bushen Tiansui decoction on hippocampal synapses in a rat model of Alzheimer's disease.
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P2860
Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function
description
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im August 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/08/31)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/08/31)
@nl
наукова стаття, опублікована в серпні 2011
@uk
مقالة علمية (نشرت في 31-8-2011)
@ar
name
Kalirin binds the NR2B subunit ...... ptic localization and function
@ast
Kalirin binds the NR2B subunit ...... ptic localization and function
@en
Kalirin binds the NR2B subunit ...... ptic localization and function
@nl
type
label
Kalirin binds the NR2B subunit ...... ptic localization and function
@ast
Kalirin binds the NR2B subunit ...... ptic localization and function
@en
Kalirin binds the NR2B subunit ...... ptic localization and function
@nl
prefLabel
Kalirin binds the NR2B subunit ...... ptic localization and function
@ast
Kalirin binds the NR2B subunit ...... ptic localization and function
@en
Kalirin binds the NR2B subunit ...... ptic localization and function
@nl
P2860
P50
P1476
Kalirin binds the NR2B subunit ...... ptic localization and function
@en
P2093
Betty A Eipper
Richard E Mains
P2860
P304
12554-12565
P356
10.1523/JNEUROSCI.3143-11.2011
P407
P577
2011-08-01T00:00:00Z