Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity - Wikidata - thesis-toulmin - TriplyDB

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

http://www.wikidata.org/entity/Q34105681

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Constitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration.Kalrn plays key roles within and outside of the nervous system SPIN90 dephosphorylation is required for cofilin-mediated actin depolymerization in NMDA-stimulated hippocampal neurons Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning.Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviors Remodeling the Dendritic Spines in the Hindlimb Representation of the Sensory Cortex after Spinal Cord Hemisection in Mice An N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions.A role for kalirin in the response of rat medium spiny neurons to cocaine.A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.RasGRF2 Rac-GEF activity couples NMDA receptor calcium flux to enhanced synaptic transmission.Modulation of behavior by scaffolding proteins of the post-synaptic density.Neuronal Rho GEFs in synaptic physiology and behavior.Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl Scaffolding proteins of the post-synaptic density contribute to synaptic plasticity by regulating receptor localization and distribution: relevance for neuropsychiatric diseases.Galectin-3 Negatively Regulates Hippocampus-Dependent Memory Formation through Inhibition of Integrin Signaling and Galectin-3 Phosphorylation RhoGTPases at the synapse: An embarrassment of choice.Alternate promoter usage generates two subpopulations of the neuronal RhoGEF Kalirin-7.Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease.Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease.

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Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

http://www.wikidata.org/entity/Q34105681

description

2011 nî lūn-bûn

@nan

2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@ast

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@en

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@nl

type

label

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@ast

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@en

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@nl

prefLabel

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@ast

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@en

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@nl

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1471-2202-12-126

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BMC Neuroscience

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Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

@en

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Betty A Eipper

http://www.w3.org/2001/XMLSchema#string

Richard E Mains

http://www.w3.org/2001/XMLSchema#string

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Genetic enhancement of learning and memory in mice

Kalirin-7 is required for synaptic structure and function

Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes

Theta oscillations in the hippocampus

Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function

NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses

Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation site

The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis

Distinct roles of NR2A and NR2B cytoplasmic tails in long-term potentiation

The subspine organization of actin fibers regulates the structure and plasticity of dendritic spines

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1471-2202-12-126

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126

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scholarly article

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10.1186/1471-2202-12-126

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12

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F Lemtiri-Chlieh

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3261125

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