Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival
about
Application of VEGFA and FGF-9 enhances angiogenesis, osteogenesis and bone remodeling in type 2 diabetic long bone regenerationMultiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1.Blood flow controls bone vascular function and osteogenesis.Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones.Soluble Factors on Stage to Direct Mesenchymal Stem Cells Fate.Complementary interplay between matrix metalloproteinase-9, vascular endothelial growth factor and osteoclast function drives endochondral bone formationSequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal developmentTumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristicsVEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice.Transient hypoxia improves matrix properties in tissue engineered cartilage.Molecular diversity of VEGF-A as a regulator of its biological activity.Fluid flow-induced soluble vascular endothelial growth factor isoforms regulate actin adaptation in osteoblastsNeuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand bindingA gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice.Neuroprotection using gene therapy to induce vascular endothelial growth factor-A expressionFibronectins in vascular morphogenesisIn vivo genome-wide analysis of multiple tissues identifies gene regulatory networks, novel functions and downstream regulatory genes for Bapx1 and its co-regulation with Sox9 in the mammalian vertebral column.Palmitoyl acyltransferase, Zdhhc13, facilitates bone mass acquisition by regulating postnatal epiphyseal development and endochondral ossification: a mouse model.Terminal differentiation is not a major determinant for the success of stem cell therapy - cross-talk between muscle-derived stem cells and host cells.Neural crest cell-derived VEGF promotes embryonic jaw extensionMammalian mRNA splice-isoform selection is tightly controlled.Solute transport in growth plate cartilage: in vitro and in vivo.Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation.Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.Enhanced Mitogenic Activity of Recombinant Human Vascular Endothelial Growth Factor VEGF121 Expressed in E. coli Origami B (DE3) with Molecular Chaperones.Role of tartrate-resistant acid phosphatase (TRAP) in long bone developmentc-Raf promotes angiogenesis during normal growth plate maturationCartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1.Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency.Inhibition of beta-catenin signaling causes defects in postnatal cartilage development.Autocrine VEGF Isoforms Differentially Regulate Endothelial Cell Behavior.The Basic Science of Bone Marrow Aspirate Concentrate in Chondral Injuries.CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1alpha expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition.Role of VEGF in organogenesis.How vascular endothelial growth factor-A (VEGF) regulates differentiation of mesenchymal stem cells.Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGFBinding to the extracellular matrix and proteolytic processing: two key mechanisms regulating vascular endothelial growth factor action.VEGF receptor signaling in vertebrate development.Mechano-regulation of alternative splicing.The roles of vascular endothelial growth factor in bone repair and regeneration.
P2860
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P2860
Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival
description
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Januar 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/01/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/01/01)
@nl
наукова стаття, опублікована в січні 2004
@uk
مقالة علمية (نشرت عام 2004)
@ar
name
Soluble VEGF isoforms are esse ...... ocyte development and survival
@ast
Soluble VEGF isoforms are esse ...... ocyte development and survival
@en
Soluble VEGF isoforms are esse ...... ocyte development and survival
@nl
type
label
Soluble VEGF isoforms are esse ...... ocyte development and survival
@ast
Soluble VEGF isoforms are esse ...... ocyte development and survival
@en
Soluble VEGF isoforms are esse ...... ocyte development and survival
@nl
prefLabel
Soluble VEGF isoforms are esse ...... ocyte development and survival
@ast
Soluble VEGF isoforms are esse ...... ocyte development and survival
@en
Soluble VEGF isoforms are esse ...... ocyte development and survival
@nl
P2093
P2860
P3181
P356
P1476
Soluble VEGF isoforms are esse ...... ocyte development and survival
@en
P2093
Christa Maes
Geert Carmeliet
Ingrid Stockmans
Karen Moermans
Nico Smets
Riet Van Looveren
Roger Bouillon
P2860
P304
P3181
P356
10.1172/JCI19383
P407
P577
2004-01-01T00:00:00Z