Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
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Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle PathwayITAM signaling by Vav family Rho guanine nucleotide exchange factors regulates interstitial transit rates of neutrophils in vivoTargeting Syk in Autoimmune Rheumatic DiseasesIntegrin-based therapeutics: biological basis, clinical use and new drugsLeukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory diseaseFunctional roles of Syk in macrophage-mediated inflammatory responsesSyk-mediated translocation of PI3Kdelta to the leading edge controls lamellipodium formation and migration of leukocytesExpression of the TEL-Syk fusion protein in hematopoietic stem cells leads to rapidly fatal myelofibrosis in miceLoss of DAP12 and FcRγ drives exaggerated IL-12 production and CD8(+) T cell response by CCR2(+) Mo-DCsStress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.FGF23 signaling impairs neutrophil recruitment and host defense during CKD.The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosisMicroglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burstSRC-mediated phosphorylation of dynamin and cortactin regulates the "constitutive" endocytosis of transferrinMultimolecular signaling complexes enable Syk-mediated signaling of CD36 internalizationNeutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infectionCritical but overlapping role of FcgammaRIII and FcgammaRIV in activation of murine neutrophils by immobilized immune complexesEndothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesionNeutrophil cell surface receptors and their intracellular signal transduction pathways.Adaptor protein is essential for insect cytokine signaling in hemocytes.Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophilsPSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.Syk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptorSLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility.The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells.Coordination of Fc receptor signaling regulates cellular commitment to phagocytosis.Intravenous immunoglobulins modulate neutrophil activation and vascular injury through FcγRIII and SHP-1.Molecular mechanisms of spontaneous and directed mast cell motility.Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo.STIM1 calcium sensor is required for activation of the phagocyte oxidase during inflammation and host defenseHuman neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseasesThe SCHOOL of nature: I. Transmembrane signaling.The N-terminal SH2 domain of Syk is required for (hem)ITAM, but not integrin, signaling in mouse platelets.Neutrophil adhesion and activation under flow.Role of NADPH oxidase in host defense against aspergillosisDAP12 is required for macrophage recruitment to the lung in response to cigarette smoke and chemotaxis toward CCL2Getting Syk: spleen tyrosine kinase as a therapeutic target.Poly(ethylene glycol)-containing hydrogels promote the release of primary granules from human blood-derived polymorphonuclear leukocytesMyeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
P2860
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P248
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P2860
Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
description
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Dezember 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2006/12/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/12/01)
@nl
наукова стаття, опублікована в грудні 2006
@uk
مقالة علمية (نشرت في ديسمبر 2006)
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name
Integrin signaling in neutroph ...... rosine-based activation motifs
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Integrin signaling in neutroph ...... rosine-based activation motifs
@en
Integrin signaling in neutroph ...... rosine-based activation motifs
@nl
type
label
Integrin signaling in neutroph ...... rosine-based activation motifs
@ast
Integrin signaling in neutroph ...... rosine-based activation motifs
@en
Integrin signaling in neutroph ...... rosine-based activation motifs
@nl
prefLabel
Integrin signaling in neutroph ...... rosine-based activation motifs
@ast
Integrin signaling in neutroph ...... rosine-based activation motifs
@en
Integrin signaling in neutroph ...... rosine-based activation motifs
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Integrin signaling in neutroph ...... rosine-based activation motifs
@en
P2093
Attila Mócsai
Clare L. Abram
Clifford A. Lowell
Lewis L. Lanier
Yongmei Hu
Zoltán Jakus
P2860
P304
P3181
P356
10.1038/NI1407
P407
P577
2006-12-01T00:00:00Z