Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation
about
The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferationModulation of human nuclear receptor LRH-1 activity by phospholipids and SHPSmall Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)Structural basis of coactivation of liver receptor homolog-1 by -cateninLRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.Chronic subordinate colony housing paradigm: a mouse model to characterize the consequences of insufficient glucocorticoid signaling.Downregulation of microRNA-30d promotes cell proliferation and invasion by targeting LRH-1 in colorectal carcinoma.alpha(1)-fetoprotein transcription factor (FTF)/liver receptor homolog-1 (LRH-1) is an essential lipogenic regulatorGenome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR.The LIM domain protein FHL2 interacts with the NR5A family of nuclear receptors and CREB to activate the inhibin-α subunit gene in ovarian granulosa cells.Estrogen-related receptor α is required for efficient human cytomegalovirus replication.Associations of NR5A2 gene polymorphisms with the clinicopathological characteristics and survival of gastric cancer.Antiproliferation activity of a small molecule repressor of liver receptor homolog 1Tumor-suppressive function of miR-139-5p in esophageal squamous cell carcinoma.Liver receptor homolog 1 is a negative regulator of the hepatic acute-phase response.Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programsNuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation.LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease.Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancerThe nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestineCompromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.Lymphatic reprogramming by Kaposi sarcoma herpes virus promotes the oncogenic activity of the virus-encoded G-protein-coupled receptor.The nuclear receptor liver receptor homolog-1 is an estrogen receptor target gene.Genetic susceptibility to pancreatic cancer.Emerging actions of the nuclear receptor LRH-1 in the gut.Structure-based discovery of antagonists of nuclear receptor LRH-1.LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer.Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips.Biliary Phospholipids Sustain Enterocyte Proliferation and Intestinal Tumor Progression via Nuclear Receptor Lrh1 in mice.Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.LRH1 as a driving factor in pancreatic cancer growthOrphan nuclear receptors as targets for drug development.The orphan nuclear receptors at their 25-year reunion.Hepatic glucose sensing and integrative pathways in the liver.Why does the gut synthesize glucocorticoids?Functional interaction between peroxisome proliferator-activated receptor gamma and beta-cateninSERBP1 Is a Component of the Liver Receptor Homologue-1 Transcriptional Complex.Survivin (BIRC5) cell cycle computational network in human no-tumor hepatitis/cirrhosis and hepatocellular carcinoma transformation.Effect of NR5A2 inhibition on pancreatic cancer stem cell (CSC) properties and epithelial-mesenchymal transition (EMT) markers.LRH-1 controls proliferation in breast tumor cells by regulating CDKN1A gene expression.
P2860
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P2860
Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation
description
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2005
@ast
im Februar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/02/08)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/02/08)
@nl
наукова стаття, опублікована в лютому 2005
@uk
name
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@ast
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@en
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@nl
type
label
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@ast
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@en
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@nl
prefLabel
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@ast
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@en
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Liver receptor homolog 1 contr ...... on cell cycle and inflammation
@en
P2093
Céline Haby
Elisabeth Fayard
Joseph Mebis
Olivia Wendling
P2860
P304
P3181
P356
10.1073/PNAS.0409756102
P407
P577
2005-02-08T00:00:00Z