Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types
about
Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activationRas-induced cellular events (review)Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1The cellular response to neuregulins is governed by complex interactions of the erbB receptor familyUnrestricted somatic stem cells from human umbilical cord blood grow in serum-free medium as spheres.Ha-Ras stabilization mediates pro-fibrotic signals in dermal fibroblasts.Beta-actin mRNA localization is regulated by signal transduction mechanisms.Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin.Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling.The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis.Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activityControl of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway.Mechanisms of disease: Fibroblasts--a new look at an old problem.Analysis of the role of the Shc and Grb2 proteins in signal transduction by the v-ErbB protein.Ca2+ channel activation by platelet-derived growth factor-induced tyrosine phosphorylation and Ras guanine triphosphate-binding proteins in rat glomerular mesangial cells.Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair.Tissue- and transformation-specific phosphotyrosyl proteins in v-erbB-transformed cellsNew insights into protein-tyrosine kinase receptor signaling complexes.Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src.The oncogenic TEL/PDGFR beta fusion protein induces cell death through JNK/SAPK pathway.Disruption of gap junctional communication by the platelet-derived growth factor is mediated via multiple signaling pathways.Regulation of interaction of ras p21 with RalGDS and Raf-1 by cyclic AMP-dependent protein kinase.Ras is not required for the interleukin 3-induced proliferation of a mouse pro-B cell line, BaF3.Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis.The molecular pathophysiology of myeloid leukaemias: Ras revisited.Differential effects of lovastatin on mitogen induced calcium influx in human cultured vascular smooth muscle cells.Regulation of platelet-derived growth factor receptor activation by afadin through SHP-2: implications for cellular morphology.PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumorigenesis by targeting multiple components of KRAS and NF-kB pathways.Clinical and cytogenetic remission induced by interferon-alpha in a patient with chronic eosinophilic leukemia associated with a unique t(3;9;5) translocation.Grb2/Sos1 complex binds to the active receptorSos-mediated nucleotide exchange of Ras (PDGF receptor:Grb2:Sos)BCR/ABL regulation of PI-3 kinase activity.
P2860
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P2860
Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types
description
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1993
@ast
im Juni 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/06/01)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/06/01)
@nl
наукова стаття, опублікована в червні 1993
@uk
مقالة علمية (نشرت في يونيو 1993)
@ar
name
Platelet-derived growth factor ...... thways in different cell types
@ast
Platelet-derived growth factor ...... thways in different cell types
@en
Platelet-derived growth factor ...... thways in different cell types
@nl
type
label
Platelet-derived growth factor ...... thways in different cell types
@ast
Platelet-derived growth factor ...... thways in different cell types
@en
Platelet-derived growth factor ...... thways in different cell types
@nl
prefLabel
Platelet-derived growth factor ...... thways in different cell types
@ast
Platelet-derived growth factor ...... thways in different cell types
@en
Platelet-derived growth factor ...... thways in different cell types
@nl
P2093
P2860
P356
P1476
Platelet-derived growth factor ...... thways in different cell types
@en
P2093
J. A. Escobedo
L. T. Williams
W. J. Fantl
P2860
P304
P356
10.1128/MCB.13.6.3706
P407
P577
1993-06-01T00:00:00Z