Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro
about
Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropismEffect of E2 envelope glycoprotein cytoplasmic domain mutations on Sindbis virus pathogenesisEntry kinetics and mouse virulence of Ross River virus mutants altered in neutralization epitopesDeduced consensus sequence of Sindbis virus strain AR339: mutations contained in laboratory strains which affect cell culture and in vivo phenotypesNonhomologous RNA-RNA recombination events at the 3' nontranslated region of the Sindbis virus genome: hot spots and utilization of nonviral sequencesChimeric Sindbis-Ross River viruses to study interactions between alphavirus nonstructural and structural regionsGenetic determinants of Sindbis virus neuroinvasivenessLethality of PE2 incorporation into Sindbis virus can be suppressed by second-site mutations in E3 and E2Sindbis virus attachment: isolation and characterization of mutants with impaired binding to vertebrate cellsMolecular analysis of neurovirulent strains of Sindbis virus that evolve during persistent infection of scid miceDivergent envelope E2 alphavirus sequences spanning amino acids 297 to 352 induce in mice virus-specific protective immunity and antibodies with complement-mediated cytolytic activityAttenuating mutations in glycoproteins E1 and E2 of Sindbis virus produce a highly attenuated strain when combined in vitroSindbis virus mutations which coordinately affect glycoprotein processing, penetration, and virulence in micePromoter for Sindbis virus RNA-dependent subgenomic RNA transcriptionA conformational change in Sindbis virus glycoproteins E1 and E2 is detected at the plasma membrane as a consequence of early virus-cell interaction.Mutational analysis of a virulence locus in the E2 glycoprotein gene of Sindbis virusA cis-acting mutation in the Sindbis virus junction region which affects subgenomic RNA synthesisMolecular basis of Sindbis virus neurovirulence in miceDetection of Ockelbo virus RNA in skin biopsies by polymerase chain reactionThe alphaviruses: gene expression, replication, and evolutionAntagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus InfectionInfection of human dendritic cells by a sindbis virus replicon vector is determined by a single amino acid substitution in the E2 glycoprotein.Virulence variation among isolates of western equine encephalitis virus in an outbred mouse modelInfectious Japanese encephalitis virus RNA can be synthesized from in vitro-ligated cDNA templates.Amino acid changes in the Sindbis virus E2 glycoprotein that increase neurovirulence improve entry into neuroblastoma cellsAn alphavirus replicon particle chimera derived from venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector.Three-dimensional structure of a membrane-containing virus.Viral determinants of age-dependent virulence of Sindbis virus for miceMechanism of altered Sindbis virus neurovirulence associated with a single-amino-acid change in the E2 Glycoprotein.Infectious enveloped RNA virus antigenic chimerasPathogenesis of encephalitis induced in newborn mice by virulent and avirulent strains of Sindbis virusThe reovirus M1 gene, encoding a viral core protein, is associated with the myocarditic phenotype of a reovirus variantGenomic regions of neurovirulence and attenuation in Theiler murine encephalomyelitis virus.A single nucleotide change in the 5' noncoding region of Sindbis virus confers neurovirulence in rats.Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer.Timeliness of proteolytic events is prerequisite for efficient functioning of the alphaviral replicase.
P2860
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P2860
Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro
description
1988 nî lūn-bûn
@nan
1988 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Molecular analysis of Sindbis ...... ombinants constructed in vitro
@ast
Molecular analysis of Sindbis ...... ombinants constructed in vitro
@en
type
label
Molecular analysis of Sindbis ...... ombinants constructed in vitro
@ast
Molecular analysis of Sindbis ...... ombinants constructed in vitro
@en
prefLabel
Molecular analysis of Sindbis ...... ombinants constructed in vitro
@ast
Molecular analysis of Sindbis ...... ombinants constructed in vitro
@en
P2093
P2860
P3181
P1433
P1476
Molecular analysis of Sindbis ...... ombinants constructed in vitro
@en
P2093
P2860
P304
P3181
P407
P577
1988-06-01T00:00:00Z