Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
about
alpha-Synuclein and neuronal cell deathSulforaphane as a potential protective phytochemical against neurodegenerative diseasesConformational equilibria in monomeric alpha-synuclein at the single-molecule levelGuidelines for the use and interpretation of assays for monitoring autophagyGenetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotesRac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2)Chaperone-mediated autophagy: molecular mechanisms and physiological relevanceNutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathwayThe selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein AlfyMutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodiesInterplay of LRRK2 with chaperone-mediated autophagyReduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's diseaseChaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMADisrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brainChaperone-mediated autophagy: a unique way to enter the lysosome worldMutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neuronsAutophagy and pattern recognition receptors in innate immunityRegulation of neuronal survival factor MEF2D by chaperone-mediated autophagyAutophagy and the ubiquitin-proteasome system: collaborators in neuroprotectionRestoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic functionTau fragmentation, aggregation and clearance: the dual role of lysosomal processingRegulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell deathDopamine-modified alpha-synuclein blocks chaperone-mediated autophagyMolecules that cause or prevent Parkinson's diseaseCell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C diseasePrediction of "hot spots" of aggregation in disease-linked polypeptidesChaperone-Mediated Autophagy and Mitochondrial Homeostasis in Parkinson's DiseaseThe autophagy-lysosomal system in subarachnoid haemorrhageNeuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein AggregationΑlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's DiseaseMetazoan Hsp70-based protein disaggregases: emergence and mechanismsDeconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purposePolyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related DiseasesCharcot-Marie-Tooth disease and intracellular trafficCurrent understanding of LRRK2 in Parkinson's disease: biochemical and structural features and inhibitor designGenetics of Parkinson's diseaseThe role of free radicals in the aging brain and Parkinson's Disease: convergence and parallelismGenetically engineered mouse models of Parkinson's disease
P2860
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P2860
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
@ast
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
@en
type
label
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
@ast
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
@en
prefLabel
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
@ast
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
@en
P2093
P921
P3181
P356
P1433
P1476
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
@en
P2093
Fredenburg R
Lansbury PT
Stefanis L
P304
P3181
P356
10.1126/SCIENCE.1101738
P407
P577
2004-08-27T00:00:00Z