Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1 - Wikidata - thesis-toulmin - TriplyDB

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

http://www.wikidata.org/entity/Q30417692

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YAP-Mediated Mechanotransduction in Skeletal Muscle Cadherin signaling: keeping cells in touch The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up YAP and TAZ: a nexus for Hippo signaling and beyond YAP/TEAD co-activator regulated pluripotency and chemoresistance in ovarian cancer initiated cells Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer Actin cytoskeleton regulates Hippo signaling Deregulation of the Hippo pathway in mouse mammary stem cells promotes mammary tumorigenesis.Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.Molecular Pathways: Hippo Signaling, a Critical Tumor Suppressor.The Hippo-YAP signaling pathway and contact inhibition of growth.Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma Two-signal requirement for growth-promoting function of Yap in hepatocytes 17-AAG suppresses growth and invasion of lung adenocarcinoma cells via regulation of the LATS1/YAP pathway.Hippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells.Prognostic Value of Yes-Associated Protein 1 (YAP1) in Various Cancers: A Meta-Analysis.Aerobic glycolysis tunes YAP/TAZ transcriptional activity A novel role for microRNA-129-5p in inhibiting ovarian cancer cell proliferation and survival via direct suppression of transcriptional co-activators YAP and TAZ.The emerging roles of YAP and TAZ in cancer YAP forms autocrine loops with the ERBB pathway to regulate ovarian cancer initiation and progression.Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration.Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients.Interaction of the EGF Receptor and the Hippo Pathway in the Diabetic Kidney.Urine miRNAs: potential biomarkers for monitoring progression of early stages of diabetic nephropathy.EGFR Signaling Regulates Maspin/SerpinB5 Phosphorylation and Nuclear Localization in Mammary Epithelial Cells.YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation 3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer.The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma.Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases Phosphorylation of Tyr188 in the WW domain of YAP1 plays an essential role in YAP1-induced cellular transformation Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis.Disease implication of hyper-Hippo signalling.Differential growth triggers mechanical feedback that elevates Hippo signaling.Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

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Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

http://www.wikidata.org/entity/Q30417692

description

2013 nî lūn-bûn

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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2013 թվականի հունվարին հրատարակված գիտական հոդված

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2013年の論文

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PNAS.1216462110

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Proceedings of the National Academy of Sciences of the United States of America

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Regulation of Hippo pathway by ...... hoinositide-dependent kinase-1

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Barry M Gumbiner

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Nam-Gyun Kim

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Run Fan

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P2860

Yap1 acts downstream of α-catenin to control epidermal proliferation

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

TEAD mediates YAP-dependent gene induction and growth control

Cell signaling by receptor tyrosine kinases

The hippo signaling pathway in development and cancer

α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1

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2569-2574

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10.1073/PNAS.1216462110

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110

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2013-01-28T00:00:00Z

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3574943

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