PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy.
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Molecular Mechanisms of Neurodegeneration in Spinal Muscular AtrophyEmerging therapies and challenges in spinal muscular atrophyC9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten.Recombinant adeno-associated virus vectors in the treatment of rare diseases.Investigational therapies for the treatment of spinal muscular atrophy.Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders.Developing therapies for spinal muscular atrophy.Advances in understanding the role of disease-associated proteins in spinal muscular atrophy.Muscle-specific expression of the RNA-binding protein Staufen1 induces progressive skeletal muscle atrophy via regulation of phosphatase tensin homolog.The SMA Trust: the role of a disease-focused research charity in developing treatments for SMA.Therapeutic strategies for spinal muscular atrophy: SMN and beyond.AAV gene delivery to the spinal cord: serotypes, methods, candidate diseases, and clinical trials.Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape.A-44G transition in SMN2 intron 6 protects patients with spinal muscular atrophy.Plastin 3 Promotes Motor Neuron Axonal Growth and Extends Survival in a Mouse Model of Spinal Muscular Atrophy.Axon outgrowth and neuronal differentiation defects after a-SMN and FL-SMN silencing in primary hippocampal cultures.
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P2860
PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
PTEN depletion decreases disea ...... el of spinal muscular atrophy.
@ast
PTEN depletion decreases disea ...... el of spinal muscular atrophy.
@en
type
label
PTEN depletion decreases disea ...... el of spinal muscular atrophy.
@ast
PTEN depletion decreases disea ...... el of spinal muscular atrophy.
@en
prefLabel
PTEN depletion decreases disea ...... el of spinal muscular atrophy.
@ast
PTEN depletion decreases disea ...... el of spinal muscular atrophy.
@en
P2093
P2860
P50
P356
P1433
P1476
PTEN depletion decreases disea ...... el of spinal muscular atrophy.
@en
P2093
Basil Sharrack
Chantal A Mutsaers
Chiara F Valori
Daniel Little
Matthew Wyles
P2860
P304
P356
10.1038/MT.2014.209
P577
2014-11-05T00:00:00Z