Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells - Wikidata - thesis-toulmin - TriplyDB

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

http://www.wikidata.org/entity/Q30859838

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Targeting Th17 Cells with Small Molecules and Small Interference RNA Generation of Aptamers with an Expanded Chemical Repertoire Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing Nucleic acid aptamers: an emerging frontier in cancer therapy Nano-Synthetic Devices in Leishmaniasis: A Bioinformatics Approach.Aptamers in diagnostics and treatment of viral infections Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapy Aptamer-Mediated Targeted Delivery of Therapeutics: An Update Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses Manipulating the in vivo immune response by targeted gene knockdown Current prospects for RNA interference-based therapies Progress toward in vivo use of siRNAs-II RNA plasticity and selectivity applicable to therapeutics and novel biosensor development Nucleic Acid Aptamers as Potential Therapeutic and Diagnostic Agents for Lymphoma.Aptamer in bioanalytical applications.Aptamer-targeted cell-specific RNA interference Multifunctional aptamer-miRNA conjugates for targeted cancer therapy.A U87-EGFRvIII cell-specific aptamer mediates small interfering RNA delivery.Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy Maleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission.Development of cell-type specific anti-HIV gp120 aptamers for siRNA delivery.Nucleotide bias observed with a short SELEX RNA aptamer library A SELEX-screened aptamer of human hepatitis B virus RNA encapsidation signal suppresses viral replication.A general RNA motif for cellular transfection.Hybrid compounds: from simple combinations to nanomachines.RNAi and small interfering RNAs in human disease therapeutic applications.Cell-type-specific aptamer and aptamer-small interfering RNA conjugates for targeted human immunodeficiency virus type 1 therapy.In vivo SELEX for Identification of Brain-penetrating Aptamers.Cell-specific aptamer-mediated targeted drug delivery DNA duplexes with hydrophobic modifications inhibit fusion between HIV-1 and cell membranes.Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras.Prodrugs for improving tumor targetability and efficiency.An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice.Cell-specific RNA aptamer against human CCR5 specifically targets HIV-1 susceptible cells and inhibits HIV-1 infectivity.Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling.Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice Optimizing siRNA delivery to the genital mucosa siRNA-based topical microbicides targeting sexually transmitted infections.UCLA1, a synthetic derivative of a gp120 RNA aptamer, inhibits entry of human immunodeficiency virus type 1 subtype C Selection strategy to generate aptamer pairs that bind to distinct sites on protein targets.

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P2860

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

http://www.wikidata.org/entity/Q30859838

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Nucleic Acids Research

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Selection, characterization an ...... siRNAs into HIV infected cells

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C Preston Neff

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Haitang Li

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Jane Zhang

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Jiehua Zhou

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John J Rossi

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Piotr Swiderski

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Ramesh Akkina

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P2860

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

Identification of host proteins required for HIV infection through a functional genomic screen

Functional polarity is introduced by Dicer processing of short substrate RNAs.

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

In vitro selection of RNA molecules that bind specific ligands

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

HIV entry and its inhibition

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen.

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3094-3109

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10.1093/NAR/GKP185

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9

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37

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51436107

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19304999

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2685106

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