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Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Afford New Opportunities in Inherited Cardiovascular Disease ModelingSex differences in the mechanisms underlying long QT syndromeCardiac disease and arrhythmogenesis: Mechanistic insights from mouse modelsTargeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f)A Pre-clinical Animal Model of Trypanosoma brucei Infection Demonstrating Cardiac DysfunctionA β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in miceZebrafish model for human long QT syndromeThe Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development.Injectable 3-D fabrication of medical electronics at the target biological tissuesIntegrating multi-scale data to create a virtual physiological mouse heart.Recent developments in the management of patients at risk for sudden cardiac death.The role of ion channelopathies in sudden cardiac death: implications for clinical practice.Speckle-tracking echocardiography elucidates the effect of pacing site on left ventricular synchronization in the normal and infarcted rat myocardium.Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart.Cardiac Arrhythmia: In vivo screening in the zebrafish to overcome complexity in drug discoverySudden cardiac death and inherited channelopathy: the basic electrophysiology of the myocyte and myocardium in ion channel disease.Deciphering Arrhythmia Mechanisms - Tools of the TradeMouse ERG K(+) channel clones reveal differences in protein trafficking and function.Triple threat: the Na+/Ca2+ exchanger in the pathophysiology of cardiac arrhythmia, ischemia and heart failure.Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmiasAbsence of the inhibitory G-protein Galphai2 predisposes to ventricular cardiac arrhythmia.Electrocardiograms corresponding to the development of myocardial infarction in anesthetized WHHLMI rabbits (Oryctolagus cuniculus), an animal model for familial hypercholesterolemia.Suppression of phosphoinositide 3-kinase signaling and alteration of multiple ion currents in drug-induced long QT syndromePredicting QT prolongation in humans during early drug development using hERG inhibition and an anaesthetized guinea-pig model.Differential hERG ion channel activity of ultrasmall gold nanoparticles.A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene.Impaired contractile function due to decreased cardiac myosin binding protein C content in the sarcomereRe-evaluating the efficacy of beta-adrenergic agonists and antagonists in long QT-3 syndrome through computational modelling.Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome.A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells.Increased persistent sodium current due to decreased PI3K signaling contributes to QT prolongation in the diabetic heartAnthropomorphizing the mouse cardiac action potential via a novel dynamic clamp method.Zebrafish genetic models for arrhythmia.Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes.On the emerging role of rabbit as human disease model and the instrumental role of novel transgenic tools.Microsystems for biomimetic stimulation of cardiac cells.Cardiac electrophysiology in mice: a matter of size.Interpreting genetic effects through models of cardiac electromechanics.Recent advances in in vivo screening for antiarrhythmic drugs.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mouse models of long QT syndrome.
@ast
Mouse models of long QT syndrome.
@en
type
label
Mouse models of long QT syndrome.
@ast
Mouse models of long QT syndrome.
@en
prefLabel
Mouse models of long QT syndrome.
@ast
Mouse models of long QT syndrome.
@en
P2860
P1476
Mouse models of long QT syndrome.
@en
P2093
Barry London
Guy Salama
P2860
P356
10.1113/JPHYSIOL.2006.118745
P407
P577
2006-10-12T00:00:00Z