Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
about
An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signalingExploring the developmental mechanisms underlying Wolf-Hirschhorn Syndrome: Evidence for defects in neural crest cell migrationPathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Protein kinase C alpha signaling inhibits cyclin D1 translation in intestinal epithelial cellsRing Finger Protein 14 is a new regulator of TCF/β-catenin-mediated transcription and colon cancer cell survival.Estradiol activates beta-catenin dependent transcription in neurons.Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer.Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screeningIntegrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron.Suppression of intestinal carcinogenesis in Apc-mutant mice by limonin.Honokiol in combination with radiation targets notch signaling to inhibit colon cancer stem cells.The canonical Wnt signalling pathway and its APC partner in colon cancer development.Wnt signaling and gastrointestinal tumorigenesis in mouse models.Role of cyclin D1 as a mediator of c-Met- and beta-catenin-induced hepatocarcinogenesisβ-Catenin C-terminal signals suppress p53 and are essential for artery formation.NHERF1/EBP50 Suppresses Wnt-β-Catenin Pathway-Driven Intestinal Neoplasia.PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression.Diminished WNT -> β-catenin -> c-MYC signaling is a barrier for malignant progression of BRAFV600E-induced lung tumorsMicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.miR-106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma.Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells.Comparison of biomarker expression between proximal and distal colorectal adenomas: The Tennessee-Indiana Adenoma Recurrence Study.Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.Efficient Wnt mediated intestinal hyperproliferation requires the cyclin D2-CDK4/6 complex.Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability.Inulin results in increased levels of beta-catenin and cyclin D1 as the adenomas increase in size from small to large in the Min/+ mouse.Evidence that bone marrow-derived mesenchymal stem cells reduce epithelial permeability following phosgene-induced acute lung injury via activation of wnt3a protein-induced canonical wnt/β-catenin signaling.Dynamics matter: differences and similarities between alternatively designed mechanisms.Protein kinase C-mediated down-regulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a phosphoinositide 3-kinase/Akt-independent, protein phosphatase 2A-dependent mechanism in intestinal epithelial cells.Extracellular calcium-sensing receptor/PTH knockout mice colons have increased Wnt/β-catenin signaling, reduced non-canonical Wnt signaling, and increased susceptibility to azoxymethane-induced aberrant crypt foci.Up-regulation of a BCL9-related beta-catenin-binding protein, B9L, in different stages of sporadic colorectal adenoma.The role of the Wnt/β-catenin signaling pathway in the proliferation of gold nanoparticle-treated human periodontal ligament stem cells
P2860
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P2860
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
@ast
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
@en
type
label
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
@ast
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
@en
prefLabel
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
@ast
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
@en
P2093
P2860
P50
P356
P1476
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.
@en
P2093
Douglas J Winton
Hans Clevers
Marc van de Wetering
Vanesa Muncan
P2860
P304
28463-28467
P356
10.1074/JBC.M500191200
P407
P577
2005-06-09T00:00:00Z