Heterologous regulation of the cardiac Ca2+ channel alpha 1 subunit by skeletal muscle beta and gamma subunits. Implications for the structure of cardiac L-type Ca2+ channels.
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Specific association of the gene product of PKD2 with the TRPC1 channelIdentification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplicationDirect interaction of the calcium sensor protein synaptotagmin I with a cytoplasmic domain of the alpha1A subunit of the P/Q-type calcium channelDistinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating.Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cellsCa2+-induced inhibition of the cardiac Ca2+ channel depends on calmodulinDirect interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptorsAbsence of the beta subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the alpha 1 subunit and eliminates excitation-contraction couplingModulation of L-type Ca2+ current but not activation of Ca2+ release by the gamma1 subunit of the dihydropyridine receptor of skeletal muscleCaV1.2 signaling complexes in the heartStructure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channelsFunctional roles of gamma2, gamma3 and gamma4, three new Ca2+ channel subunits, in P/Q-type Ca2+ channel expressed in Xenopus oocytesExcitation-contraction coupling in skeletal muscle of a mouse lacking the dihydropyridine receptor subunit gamma1Altered inactivation of Ca2+ current and Ca2+ release in mouse muscle fibers deficient in the DHP receptor gamma1 subunitThe ß subunit of voltage-gated Ca2+ channelsMembrane-associated guanylate kinase-like properties of beta-subunits required for modulation of voltage-dependent Ca2+ channelsProtein kinase A modulation of CaV1.4 calcium channelsCharacterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition.Phospholemman modulates the gating of cardiac L-type calcium channels.Recovery of Ca2+ current, charge movements, and Ca2+ transients in myotubes deficient in dihydropyridine receptor beta 1 subunit transfected with beta 1 cDNA.Ca2+ current activation rate correlates with alpha 1 subunit density.The beta subunit controls the gating and dihydropyridine sensitivity of the skeletal muscle Ca2+ channel.T-type and N-type calcium channels of Xenopus oocytes: evidence for specific interactions with beta subunitsCa(2+)-dependent inactivation of a cloned cardiac Ca2+ channel alpha 1 subunit (alpha 1C) expressed in Xenopus oocytes.Molecular origin of the L-type Ca2+ current of skeletal muscle myotubes selectively deficient in dihydropyridine receptor beta1a subunitMutations in the EF-hand motif impair the inactivation of barium currents of the cardiac alpha1C channelDifferential regulation of skeletal muscle L-type Ca2+ current and excitation-contraction coupling by the dihydropyridine receptor beta subunit.Critical determinants of Ca(2+)-dependent inactivation within an EF-hand motif of L-type Ca(2+) channels.Expression of the alpha(2)delta subunit interferes with prepulse facilitation in cardiac L-type calcium channels.Differential modulation of cardiac Ca2+ channel gating by beta-subunits.Amino acid substitutions in the pore of the Ca(V)1.2 calcium channel reduce barium currents without affecting calcium currentsCardiac L-type calcium channel (Cav1.2) associates with gamma subunits.Genetic and developmental characterization of Dmca1D, a calcium channel alpha1 subunit gene in Drosophila melanogaster.Critical role of conserved proline residues in the transmembrane segment 4 voltage sensor function and in the gating of L-type calcium channels.Impact of phosphomimetic and non-phosphorylatable mutations of phospholemman on L-type calcium channels gating in HEK 293T cells.Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel gamma subunitFunctional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels.Feedback inhibition of Ca2+ channels by Ca2+ depends on a short sequence of the C terminus that does not include the Ca2+ -binding function of a motif with similarity to Ca2+ -binding domains.Gating modifier toxins reveal a conserved structural motif in voltage-gated Ca2+ and K+ channelsRegulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).
P2860
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P2860
Heterologous regulation of the cardiac Ca2+ channel alpha 1 subunit by skeletal muscle beta and gamma subunits. Implications for the structure of cardiac L-type Ca2+ channels.
description
1991 nî lūn-bûn
@nan
1991 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
name
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@ast
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@en
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@nl
type
label
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@ast
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@en
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@nl
prefLabel
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@ast
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@en
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@nl
P2093
P1476
Heterologous regulation of the ...... cardiac L-type Ca2+ channels.
@en
P2093
Birnbaumer L
Lacerda AE
Perez-Reyes E
Schuster G
P304
21943-21947
P407
P577
1991-11-01T00:00:00Z