Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to megakaryocytes.
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A critical role for the transcription factor Scl in platelet production during stress thrombopoiesisTranscription factors in late megakaryopoiesis and related platelet disordersPluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical applicationStress-activated cap'n'collar transcription factors in aging and human diseaseCharacterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis.DNA Methylation Dynamics of Human Hematopoietic Stem Cell DifferentiationPrimary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta 3 signalingThe megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesisExpression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2.Mechanisms of organelle transport and capture along proplatelets during platelet production.Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticlesIntrinsic impaired proplatelet formation and microtubule coil assembly of megakaryocytes in a mouse model of Bernard-Soulier syndrome.The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis.The biogenesis of platelets from megakaryocyte proplatelets.Platelet formationThrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.Molecular determinants for small Maf protein control of platelet productionMegakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets.Does size matter in platelet production?NF-E2 p45 is important for establishing normal function of platelets.ROS-mediated platelet generation: a microenvironment-dependent manner for megakaryocyte proliferation, differentiation, and maturation.The effect of amifostine on differentiation of the human megakaryoblastic Dami cell line.Hyaluronan Depolymerization by Megakaryocyte Hyaluronidase-2 Is Required for Thrombopoiesis.NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytesGfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes.Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation.Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesisInduction of platelet formation from megakaryocytoid cells by nitric oxide.The incredible journey: From megakaryocyte development to platelet formation.Cytoskeletal mechanics of proplatelet maturation and platelet release.MafG sumoylation is required for active transcriptional repression.Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released.Regulatory effects of TLR2 on megakaryocytic cell function.Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytesCanonical Wnt signaling in megakaryocytes regulates proplatelet formation.Dynamin 3 participates in the growth and development of megakaryocytes.The transcription factor, Nuclear factor, erythroid 2 (Nfe2), is a regulator of the oxidative stress response during Danio rerio development.Megakaryocytes compensate for Kit insufficiency in murine arthritis.
P2860
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P2860
Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to megakaryocytes.
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Mice lacking transcription fac ...... s intrinsic to megakaryocytes.
@ast
Mice lacking transcription fac ...... s intrinsic to megakaryocytes.
@en
type
label
Mice lacking transcription fac ...... s intrinsic to megakaryocytes.
@ast
Mice lacking transcription fac ...... s intrinsic to megakaryocytes.
@en
prefLabel
Mice lacking transcription fac ...... s intrinsic to megakaryocytes.
@ast
Mice lacking transcription fac ...... s intrinsic to megakaryocytes.
@en
P2093
P1433
P1476
Mice lacking transcription fac ...... s intrinsic to megakaryocytes.
@en
P2093
P304
P407
P577
1998-09-01T00:00:00Z