Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.
about
Fibroblast growth factor signaling in skeletal development and disease3-dimensional imaging modalities for phenotyping genetically engineered miceCraniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant miceQuantification of facial skeletal shape variation in fibroblast growth factor receptor-related craniosynostosis syndromes.Heterotopic ossifications in a mouse model of albright hereditary osteodystrophyFGF/FGFR signaling coordinates skull development by modulating magnitude of morphological integration: evidence from Apert syndrome mouse modelsBeyond the closed suture in apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth.Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.Closing the Gap: Genetic and Genomic Continuum from Syndromic to Nonsyndromic Craniosynostoses.p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice.The effect of a Beare-Stevenson syndrome Fgfr2 Y394C mutation on early craniofacial bone volume and relative bone mineral density in mice.Molecular mechanisms of midfacial developmental defects.Further analysis of the Crouzon mouse: effects of the FGFR2(C342Y) mutation are cranial bone-dependentFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeUnderstanding craniosynostosis as a growth disorderQuantification of shape and cell polarity reveals a novel mechanism underlying malformations resulting from related FGF mutations during facial morphogenesis.A Ser252Trp mutation in fibroblast growth factor receptor 2 (FGFR2) mimicking human Apert syndrome reveals an essential role for FGF signaling in the regulation of endochondral bone formation.Deformed Skull Morphology Is Caused by the Combined Effects of the Maldevelopment of Calvarias, Cranial Base and Brain in FGFR2-P253R Mice Mimicking Human Apert Syndrome.Analysis of the Fgfr2C342Y mouse model shows condensation defects due to misregulation of Sox9 expression in prechondrocytic mesenchyme.Embryonic craniofacial bone volume and bone mineral density in Fgfr2(+/P253R) and nonmutant mice.The role of vertebrate models in understanding craniosynostosis.Hand in glove: brain and skull in development and dysmorphogenesis.The molecular and cellular basis of Apert syndrome.Inducible activation of FGFR2 in adult mice promotes bone formation after bone marrow ablation.Tracheal cartilaginous sleeves in children with syndromic craniosynostosis.Signaling networks in joint development.Brain phenotypes in two FGFR2 mouse models for Apert syndrome.Germline Stem Cell Competition, Mutation Hot Spots, Genetic Disorders, and Older Fathers.FGFR2c-mediated ERK-MAPK activity regulates coronal suture development.Rapid re-synostosis following suturectomy in pediatric mice is age and location dependent.FGFR2 mutation confers a less drastic gain of function in mesenchymal stem cells than in fibroblasts.Mouse models of Apert syndrome.Algorithm to assess cranial suture fusion with varying and discontinuous mineral density.Morphological evaluation of cranial and maxillary shape differences of the brachymorphic mouse with spontaneous malocclusion using three-dimensional micro-computed tomography.Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model.Postnatal brain and skull growth in an Apert syndrome mouse model.Research advances in Apert syndromeQuantification of gene expression patterns to reveal the origins of abnormal morphogenesis
P2860
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P2860
Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2
@nl
Activation of p38 MAPK pathway ...... t syndrome Fgfr2(+P253R) mice.
@ast
Activation of p38 MAPK pathway ...... t syndrome Fgfr2(+P253R) mice.
@en
type
label
Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2
@nl
Activation of p38 MAPK pathway ...... t syndrome Fgfr2(+P253R) mice.
@ast
Activation of p38 MAPK pathway ...... t syndrome Fgfr2(+P253R) mice.
@en
prefLabel
Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2
@nl
Activation of p38 MAPK pathway ...... t syndrome Fgfr2(+P253R) mice.
@ast
Activation of p38 MAPK pathway ...... t syndrome Fgfr2(+P253R) mice.
@en
P2093
P2860
P356
P1476
Activation of p38 MAPK pathway ...... t syndrome Fgfr2(+P253R) mice.
@en
P2093
Cheryl A Hill
David L Huso
Inga Peter
Joan T Richtsmeier
Neus Martinez-Abadias
Victoria L Uhlhorn
Xueyan Zhou
Yingli Wang
P2860
P2888
P356
10.1186/1471-213X-10-22
P577
2010-02-22T00:00:00Z
P6179
1033710221