Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
about
Visualizing genome and systems biology: technologies, tools, implementation techniques and trends, past, present and futureExpanding the scope of site-specific recombinases for genetic and metabolic engineeringAttachment site recognition and regulation of directionality by the serine integrasesThe therapeutic potential of ΦC31 integrase as a gene therapy systemMutants of Cre recombinase with improved accuracyMutational analysis of highly conserved residues in the phage phiC31 integrase reveals key amino acids necessary for the DNA recombinationBioluminescence imaging allows monitoring hepatitis C virus core protein inhibitors in miceImpact of hydrodynamic injection and phiC31 integrase on tumor latency in a mouse model of MYC-induced hepatocellular carcinomaUltrasound-targeted hepatic delivery of factor IX in hemophiliac mice.Next-generation site-directed transgenesis in the malaria vector mosquito Anopheles gambiae: self-docking strains expressing germline-specific phiC31 integrase.Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activityUse of phage φC31 integrase as a tool for zebrafish genome manipulation.PhiC31 integrase induces efficient site-specific recombination in the Capra hircus genome.Biosafety assessment of site-directed transgene integration in human umbilical cord-lining cells.Transgene autoexcision in switchgrass pollen mediated by the Bxb1 recombinaseKinetics and longevity of ΦC31 integrase in mouse liver and cultured cellsGeneration of induced pluripotent stem cells using site-specific integration with phage integraseHighly modular bow-tie gene circuits with programmable dynamic behaviourSerine integrase chimeras with activity in E. coli and HeLa cells.Adeno-associated virus: a key to the human genome?Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.Adjusting the attB site in donor plasmid improves the efficiency of ΦC31 integrase systemTransgenic Anopheles stephensi coexpressing single-chain antibodies resist Plasmodium falciparum development.Comparison of transgene expression in Aedes aegypti generated by mariner Mos1 transposition and ΦC31 site-directed recombination.Enhanced heterologous protein productivity by genome reduction in Lactococcus lactis NZ9000.Temporal self-regulation of transposition through host-independent transposase rodlet formation.Targeted approaches for gene therapy and the emergence of engineered meganucleases.Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.Tumorigenicity of pluripotent stem cells: biological insights from molecular imagingRecombinase technology: applications and possibilitiesViral hybrid vectors for somatic integration - are they the better solution?Exogenous enzymes upgrade transgenesis and genetic engineering of farm animals.Genome Editing Techniques and Their Therapeutic Applications.Using the Cre/lox system for targeted integration into the human genome: loxFAS-loxP pairing and delayed introduction of Cre DNA improve gene swapping efficiency.PhiC31 integrase induces efficient site-specific excision in zebrafish.Long-term expression of human coagulation factor VIII in a tolerant mouse model using the φC31 integrase system.Long-term phenotypic correction in factor IX knockout mice by using ΦC31 integrase-mediated gene therapy.Engineering altered protein-DNA recognition specificity.
P2860
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P2860
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
@ast
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
@en
type
label
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
@ast
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
@en
prefLabel
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
@ast
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
@en
P2093
P2860
P356
P1433
P1476
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity.
@en
P2093
Annahita Keravala
Bhaskar Thyagarajan
Eric C Olivares
Lauren E Woodard
Michele P Calos
Solomon Lee
Vanessa E Gabrovsky
P2860
P304
P356
10.1038/MT.2008.241
P577
2008-11-11T00:00:00Z