Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: the amygdala is by far the most sensitive.
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Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice.The molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersNeurosteroids: endogenous role in the human brain and therapeutic potentialsCyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenoloneEndogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C diseaseNeurosteroid regulation of central nervous system developmentAge relationships and sex differences in serum levels of pregnenolone and 17-hydroxypregnenolone in healthy subjectsProof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophreniaPregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunitNeuroactive Steroids are Altered in Schizophrenia and Bipolar Disorder: Relevance to Pathophysiology and TherapeuticsAntipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotectionCharacterization of the convulsant action of pregnenolone sulfateGABA(A) receptors and their associated proteins: implications in the etiology and treatment of schizophrenia and related disorders.Neurosteroid transport by the organic solute transporter OSTα-OSTβ.Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation.The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: distinct mechanisms?A role for picomolar concentrations of pregnenolone sulfate in synaptic activity-dependent Ca2+ signaling and CREB activationThe NMDA receptor as a target for cognitive enhancementA steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivityRoles of sigma-1 receptors in Alzheimer's disease.Enhancement of basolateral amygdaloid neuronal dendritic arborization following Bacopa monniera extract treatment in adult rats.Neurosteroids and GABA-A Receptor Function.A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protonsPregnenolone sulfate as a modulator of synaptic plasticity.Endocrine and metabolic changes in human aging.Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjectsPotentially predictive and manipulable blood serum correlates of aging in the healthy human male: progressive decreases in bioavailable testosterone, dehydroepiandrosterone sulfate, and the ratio of insulin-like growth factor 1 to growth hormone.Effects of acute and chronic administration of neurosteroid dehydroepiandrosterone sulfate on neuronal excitability in mice.Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus.Sigma receptors [σRs]: biology in normal and diseased statesThe Singapore flagship programme in translational and clinical research in psychosis.Neuroendocrine Regulation of Anxiety: Beyond the Hypothalamic-Pituitary-Adrenal Axis.Human neuroblastoma SH-SY5Y cell line: neurosteroid-producing cell line relying on cytoskeletal organization.Low concentrations of neuroactive steroids alter kinetics of [3H]ifenprodil binding to the NMDA receptor in rat frontal cortexNeurosteroids in the Hippocampus: Neuronal Plasticity and Memory.Enhancement of Amygdaloid Neuronal Dendritic Arborization by Fresh Leaf Juice of Centella asiatica (Linn) During Growth Spurt Period in Rats.Steroid structure and pharmacological properties determine the anti-amnesic effects of pregnenolone sulphate in the passive avoidance task in rats.Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors.Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain.Minimizing the effects of multicollinearity in the polynomial regression of age relationships and sex differences in serum levels of pregnenolone sulfate in healthy subjects.
P2860
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P2860
Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: the amygdala is by far the most sensitive.
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Pregnenolone sulfate enhances ...... is by far the most sensitive.
@ast
Pregnenolone sulfate enhances ...... is by far the most sensitive.
@en
type
label
Pregnenolone sulfate enhances ...... is by far the most sensitive.
@ast
Pregnenolone sulfate enhances ...... is by far the most sensitive.
@en
prefLabel
Pregnenolone sulfate enhances ...... is by far the most sensitive.
@ast
Pregnenolone sulfate enhances ...... is by far the most sensitive.
@en
P2093
P2860
P356
P1476
Pregnenolone sulfate enhances ...... is by far the most sensitive.
@en
P2093
P2860
P304
10806-10810
P356
10.1073/PNAS.92.23.10806
P407
P577
1995-11-01T00:00:00Z