Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation
about
A cluster of hematopoietic serine protease genes is found on the same chromosomal band as the human alpha/delta T-cell receptor locusHOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox proteinTwenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clusteringAnalysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpointsThe treatment of thrombotic thrombocytopenic purpura: plasma infusion or exchange?Biology and treatment of adult acute lymphoblastic leukemiaAn efficient and robust statistical modeling approach to discover differentially expressed genes using genomic expression profiles.Clinical and biological importance of cytogenetic abnormalities in childhood and adult acute lymphoblastic leukemia.The t(10;14)(q24;q11) of T-cell acute lymphoblastic leukemia juxtaposes the delta T-cell receptor with TCL3, a conserved and activated locus at 10q24.Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia.Pediatric T-cell acute lymphoblastic leukemia.S1 nuclease hypersensitive sites in an oligopurine/oligopyrimidine DNA from the t(10;14) breakpoint cluster region.Dysregulation of HOX11 by chromosome translocations in T-cell acute lymphoblastic leukemia: a paradigm for homeobox gene involvement in human cancer.TCR delta gene rearrangements in acute myeloid leukemia with T-lymphoid antigen expression.G-quadruplex structures formed at the HOX11 breakpoint region contribute to its fragility during t(10;14) translocation in T-cell leukemia.Enforced expression of HOX11 is associated with an immature phenotype in J2E erythroid cells.V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies.
P2860
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P2860
Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation
description
1989 nî lūn-bûn
@nan
1989 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
name
Clustering of breakpoints on c ...... 0;14) chromosome translocation
@ast
Clustering of breakpoints on c ...... 0;14) chromosome translocation
@en
type
label
Clustering of breakpoints on c ...... 0;14) chromosome translocation
@ast
Clustering of breakpoints on c ...... 0;14) chromosome translocation
@en
prefLabel
Clustering of breakpoints on c ...... 0;14) chromosome translocation
@ast
Clustering of breakpoints on c ...... 0;14) chromosome translocation
@en
P2093
P2860
P356
P1476
Clustering of breakpoints on c ...... 0;14) chromosome translocation
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.11.4161
P407
P577
1989-06-01T00:00:00Z