Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation. - Wikidata - thesis-toulmin - TriplyDB

Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation.

Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation.

http://www.wikidata.org/entity/Q33897727

about

Phosphate homeostasis and its role in bone health Tissue-nonspecific alkaline phosphatase deficiency causes abnormal craniofacial bone development in the Alpl(-/-) mouse model of infantile hypophosphatasia Phosphate interacts with PTHrP to regulate endochondral bone formation Phosphate sensing.Role of Fas and Treg cells in fracture healing as characterized in the fas-deficient (lpr) mouse model of lupus.SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates Early skeletal and biochemical alterations in pediatric chronic kidney disease.β-elemene reverses the drug resistance of A549/DDP lung cancer cells by activating intracellular redox system, decreasing mitochondrial membrane potential and P-glycoprotein expression, and inducing apoptosis Intracellular modulation of signaling pathways by annexin A6 regulates terminal differentiation of chondrocytes.Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism c-Raf promotes angiogenesis during normal growth plate maturation 1,25-Dihydroxyvitamin D Alone Improves Skeletal Growth, Microarchitecture, and Strength in a Murine Model of XLH, Despite Enhanced FGF23 Expression.Disrupted mitochondrial function in the Opa3L122P mouse model for Costeff Syndrome impairs skeletal integrity.Sox9 reprogrammed dermal fibroblasts undergo hypertrophic differentiation in vitro and trigger endochondral ossification in vivo.Effect of bisphosphonates on the rapidly growing male murine skeleton.Hypophosphatemic rickets due to perturbations in renal tubular function.Tissue Nonspecific Alkaline Phosphatase (TNAP) Regulates Cranial Base Growth and Synchondrosis Maturation.The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.Raf Kinases Are Essential for Phosphate Induction of ERK1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development.Hypersensitivity of mtDNA-depleted cells to staurosporine-induced apoptosis: roles of Bcl-2 downregulation and cathepsin B.Effects of extracellular phosphate on gene expression in murine osteoblasts.Phosphate (Pi)-regulated heterodimerization of the high-affinity sodium-dependent Pi transporters PiT1/Slc20a1 and PiT2/Slc20a2 underlies extracellular Pi sensing independently of Pi uptake.Increased Circulating FGF23 Does Not Lead to Cardiac Hypertrophy in the Male Hyp Mouse Model of XLH.Dietary phosphate modifies lifespan in Drosophila.Hypophosphatemia Regulates Molecular Mechanisms of Circadian Rhythm

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P2860

Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation.

http://www.wikidata.org/entity/Q33897727

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Phosphate-induced apoptosis of ...... t upon Erk1/2 phosphorylation.

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Phosphate-induced apoptosis of ...... t upon Erk1/2 phosphorylation.

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Phosphate-induced apoptosis of ...... t upon Erk1/2 phosphorylation.

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Phosphate-induced apoptosis of ...... t upon Erk1/2 phosphorylation.

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JBC.M109.098616

P1433

Journal of Biological Chemistry

P1476

Phosphate-induced apoptosis of ...... t upon Erk1/2 phosphorylation.

@en

P2093

Alena Zalutskaya

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Eric D Zhu

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Marie B Demay

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Susanne U Miedlich

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P2860

SLC34A3 mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria predict a key role for the sodium-phosphate cotransporter NaPi-IIc in maintaining phosphate homeostasis

Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Extracellular Ca(2+)-sensing receptors modulate matrix production and mineralization in chondrogenic RCJ3.1C5.18 cells

Phosphate ions mediate chondrocyte apoptosis through a plasma membrane transporter mechanism.

Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes.

Phosphate stimulates matrix Gla protein expression in chondrocytes through the extracellular signal regulated kinase signaling pathway

A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes

Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis.

Phosphate is a specific signal for ATDC5 chondrocyte maturation and apoptosis-associated mineralization: possible implication of apoptosis in the regulation of endochondral ossification.

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18270-18275

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10.1074/JBC.M109.098616

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24

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285

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2010-04-19T00:00:00Z

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43201701

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20404333

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phosphorylation

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2881751

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