Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells. - Wikidata - thesis-toulmin - TriplyDB

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

http://www.wikidata.org/entity/Q33938894

about

Mitochondrial metabolic remodeling in response to genetic and environmental perturbations Defects in mitochondrial metabolism and cancer Oncometabolites: Unconventional triggers of oncogenic signalling cascades Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents Mitochondrial Deficiencies in the Predisposition to Paraganglioma The oncometabolite fumarate promotes pseudohypoxia through noncanonical activation of NF-κB signaling Oncometabolites: linking altered metabolism with cancer.Fumarate induces redox-dependent senescence by modifying glutathione metabolism.Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism.Targeting arginine-dependent cancers with arginine-degrading enzymes: opportunities and challenges.Subcellular functions of proteins under fluorescence single-cell microscopy.Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).Altered metabolite levels in cancer: implications for tumour biology and cancer therapy.Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM).Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects.Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells.Global metabolomic profiling of uterine leiomyomas.Targeting Metabolism for Cancer Therapy.The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.Metabolic implications of hypoxia and pseudohypoxia in pheochromocytoma and paraganglioma.Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress.

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Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

http://www.wikidata.org/entity/Q33938894

description

2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

@ast

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

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type

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Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

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Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

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Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

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Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

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Cancer & Metabolism

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Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells

@en

P2093

Ann Hedley

http://www.w3.org/2001/XMLSchema#string

Christian Frezza

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David G Watson

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Elaine D MacKenzie

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Gabriela Kalna

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Liang Zheng

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Peter Szlosarek

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Saadia A Karim

http://www.w3.org/2001/XMLSchema#string

P2860

Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion

Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer.

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer.

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

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10.1186/2049-3002-1-12

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