Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma.
about
Malignant mesotheliomaTreatment rationale and study design for a phase III, double-blind, placebo-controlled study of maintenance pemetrexed plus best supportive care versus best supportive care immediately following induction treatment with pemetrexed plus cisplatin forTRAIL and proteasome inhibitors combination induces a robust apoptosis in human malignant pleural mesothelioma cells through Mcl-1 and Akt protein cleavagesProteasome inhibitor MG132 induces apoptosis and inhibits invasion of human malignant pleural mesothelioma cellsPemetrexed disodium in combination with cisplatin versus other cytotoxic agents or supportive care for the treatment of malignant pleural mesotheliomaRadiotherapy for malignant pleural mesotheliomaFibulin-3 as a blood and effusion biomarker for pleural mesothelioma.Depressogenic effects of medications: a reviewOrotate phosphoribosyltransferase is overexpressed in malignant pleural mesothelioma: Dramatically responds one case in high OPRT expressionPemetrexed Maintenance Therapy Following Bevacizumab-Containing First-Line Chemotherapy in Advanced Malignant Pleural Mesothelioma: A Case Report and Literatures ReviewPalliative cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion: current clinical practice or misnomer?Advances in the diagnosis, treatment and prognosis of malignant pleural mesotheliomaHedgehog Signaling in Malignant Pleural MesotheliomaMesothelioma treatment: Are we on target? A reviewMalignant pleural mesothelioma: incidence, etiology, diagnosis, treatment, and occupational healthSerine, glycine and one-carbon units: cancer metabolism in full circleLooking up: Recent advances in understanding and treating peritoneal carcinomatosisNew insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomasSerum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysisMalignant mesothelioma of the pleura with desmoplastic histology: a case series and literature review.Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targetsBRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma.MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.Role of Akt signaling in resistance to DNA-targeted therapyThe evolution of the diminishing role of extrapleural pneumonectomy in the surgical management of malignant pleural mesotheliomaPemetrexed clinical studies in performance status 2 patients with non-small cell lung cancer (Review)Advances in anticancer immunotoxin therapyA phase I study of pemetrexed (LY231514) supplemented with folate and vitamin B12 in Japanese patients with solid tumoursTrial on refinement of early stage non-small cell lung cancer. Adjuvant chemotherapy with pemetrexed and cisplatin versus vinorelbine and cisplatin: the TREAT protocolGender-Specific Molecular and Clinical Features Underlie Malignant Pleural MesotheliomaBiomarkers and prognostic factors for mesotheliomaFibulin-3 as a biomarker of response to treatment in malignant mesotheliomaMalignant mesothelioma: facts, myths, and hypothesesReactive oxygen species a double-edged sword for mesotheliomaCurrent issues in malignant pleural mesothelioma evaluation and managementGuidelines for the diagnosis and treatment of malignant pleural mesotheliomaLatest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapiesMolecular resistance fingerprint of pemetrexed and platinum in a long-term survivor of mesotheliomaBAK and NOXA are critical determinants of mitochondrial apoptosis induced by bortezomib in mesotheliomaVariation in drug sensitivity of malignant mesothelioma cell lines with substantial effects of selenite and bortezomib, highlights need for individualized therapy
P2860
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P2860
Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@ast
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@en
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@nl
type
label
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@ast
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@en
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@nl
prefLabel
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@ast
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@en
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@nl
P2093
P356
P1476
Phase III study of pemetrexed ...... alignant pleural mesothelioma.
@en
P2093
Christian Manegold
Claude Denham
Clet Niyikiza
James J Rusthoven
James Symanowski
Michael Boyer
Nicholas J Vogelzang
Paolo Paoletti
Pierre Ruffie
P304
P356
10.1200/JCO.2003.11.136
P407
P577
2003-07-01T00:00:00Z