Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes. - Wikidata - thesis-toulmin - TriplyDB

Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes.

Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes.

http://www.wikidata.org/entity/Q34279130

about

MYC, Metabolism, and Cancer Decoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chain Two-way communication between the metabolic and cell cycle machineries: the molecular basis Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence"Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability From Krebs to clinic: glutamine metabolism to cancer therapy.Endothelial PFKFB3 plays a critical role in angiogenesis.Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells GPS-ARM: computational analysis of the APC/C recognition motif by predicting D-boxes and KEN-boxes.Uncoupling the Warburg effect from cancer.Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle.Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine Phosphorylation of pyruvate kinase M2 and lactate dehydrogenase A by fibroblast growth factor receptor 1 in benign and malignant thyroid tissue.Linking metabolism and cell cycle progression via the APC/CCdh1 and SCFβTrCP ubiquitin ligases Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells.Targeting glucose metabolism for cancer therapy.The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1.A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes.Manganese superoxide dismutase regulates a metabolic switch during the mammalian cell cycle.Malate dehydrogenase-2 inhibitor LW6 promotes metabolic adaptations and reduces proliferation and apoptosis in activated human T-cells.Metabolic regulation of T lymphocytes.Aβ Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal Survival Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis Activated lymphocytes as a metabolic model for carcinogenesis.Increased concentrations of fructose 2,6-bisphosphate contribute to the Warburg effect in phosphatase and tensin homolog (PTEN)-deficient cells.Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis.Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy.Processive ubiquitin chain formation by the anaphase-promoting complex.Structural insights into anaphase-promoting complex function and mechanism.Metabolic sensors and their interplay with cell signalling and transcription.Regeneration of pancreatic beta-cell mass for the treatment of diabetes.Fulfilling the metabolic requirements for cell proliferation.Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation.Glucose and glutamine metabolism control by APC and SCF during the G1-to-S phase transition of the cell cycle.Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase.New Functions of APC/C Ubiquitin Ligase in the Nervous System and Its Role in Alzheimer's Disease.Glutamine antagonist-mediated immune suppression decreases pathology but delays virus clearance in mice during nonfatal alphavirus encephalomyelitis.

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Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes.

http://www.wikidata.org/entity/Q34279130

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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type

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Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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Anaphase-promoting complex/cyc ...... phase in human T lymphocytes.

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PNAS.1012362107

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Proceedings of the National Academy of Sciences of the United States of America

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Anaphase-promoting complex/cyc ...... S phase in human T lymphocytes

@en

P2093

Christoph A Schmitt

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Joel De Leon

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Leanne Boorn

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Nanci Frakich

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Nicola Davis

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Salvador Moncada

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P2860

The function of APC/CCdh1 in cell cycle and beyond

Geminin, an inhibitor of DNA replication, is degraded during mitosis

The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

ExPASy: The proteomics server for in-depth protein knowledge and analysis

Fructose-2,6-bisphosphate and control of carbohydrate metabolism in eukaryotes

The anaphase-promoting complex: proteolysis in mitosis and beyond

Exploiting the PI3K/AKT pathway for cancer drug discovery

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation

Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation.

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18868-18873

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scholarly article

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44

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107

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Miriam Palacios

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2010-10-04T00:00:00Z

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47336610

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20921411

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2973876

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