Elimination of background recombination: somatic induction of Cre by combined transcriptional regulation and hormone binding affinity.
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Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestineOncogenic Kras initiates leukemia in hematopoietic stem cellsCell-of-Origin of Cancer versus Cancer Stem Cells: Assays and InterpretationsCdx2 determines the fate of postnatal intestinal endodermCul4A is required for hematopoietic cell viability and its deficiency leads to apoptosisLkb1 deficiency alters goblet and paneth cell differentiation in the small intestineLarge-scale clonal analysis reveals unexpected complexity in surface ectoderm morphogenesisA novel estrogen receptor intramolecular folding-based titratable transgene expression system.Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladderReversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.Conditional gene expression systems in the transgenic rat brain.β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.The epigenetic regulator CXXC finger protein 1 is essential for murine hematopoiesis.HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.An intramolecular folding sensor for imaging estrogen receptor-ligand interactions.E-cadherin can limit the transforming properties of activating β-catenin mutations.Bcl-2 is a critical mediator of intestinal transformationIntestinal homeostasis and neoplasia studied using conditional transgenesis.Beyond knockouts: cre resources for conditional mutagenesis.Cardiac fibrosis in mice expressing an inducible myocardial-specific Cre driver.HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiationNew insights into mechanisms of stem cell daughter fate determination in regenerative tissues.Lineage analysis of epidermal stem cells.Determining the fate of hepatic cells by lineage tracing: facts and pitfalls.Protocols for Analyzing the Role of Paneth Cells in Regenerating the Murine Intestine using Conditional Cre-lox Mouse ModelsAcute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formationDefining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.Potential Pitfalls of the Mx1-Cre System: Implications for Experimental Modeling of Normal and Malignant Hematopoiesis.V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a.Evidence for a crucial role of paneth cells in mediating the intestinal response to injury.A CreER-based random induction strategy for modeling translocation-associated sarcomas in mice.A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice.Mitochondrial Dynamics is a Distinguishing Feature of Skeletal Muscle Fiber Types and Regulates Organellar Compartmentalization.Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability.Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation.Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner.Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues.A single dividing cell population with imbalanced fate drives oesophageal tumour growth.Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.Inducible disruption of the c-myb gene allows allogeneic bone marrow transplantation without irradiation.
P2860
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P2860
Elimination of background recombination: somatic induction of Cre by combined transcriptional regulation and hormone binding affinity.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Elimination of background reco ...... and hormone binding affinity.
@ast
Elimination of background reco ...... and hormone binding affinity.
@en
Elimination of background reco ...... and hormone binding affinity.
@nl
type
label
Elimination of background reco ...... and hormone binding affinity.
@ast
Elimination of background reco ...... and hormone binding affinity.
@en
Elimination of background reco ...... and hormone binding affinity.
@nl
prefLabel
Elimination of background reco ...... and hormone binding affinity.
@ast
Elimination of background reco ...... and hormone binding affinity.
@en
Elimination of background reco ...... and hormone binding affinity.
@nl
P2093
P2860
P356
P1476
Elimination of background reco ...... n and hormone binding affinity
@en
P2093
Carol Houghton
Douglas J Winton
Elizabeth Clayton
Heather Ireland
Louise Howard
P2860
P356
10.1093/NAR/GNH090
P407
P50
P577
2004-07-01T00:00:00Z