Disruption of base pairing between the 5' splice site and the 5' end of U1 snRNA is required for spliceosome assembly.
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Involvement of U1 small nuclear ribonucleoproteins (snRNP) in 5' splice site-U1 snRNP interactionThe human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitroPhosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2.The canonical GU dinucleotide at the 5' splice site is recognized by p220 of the U5 snRNP within the spliceosomeThe C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5' splice siteSite-specific crosslinking of mammalian U11 and u6atac to the 5' splice site of an AT-AC intronA novel yeast U2 snRNP protein, Snu17p, is required for the first catalytic step of splicing and for progression of spliceosome assembly.In vitro interaction between human immunodeficiency virus type 1 Rev protein and splicing factor ASF/SF2-associated protein, p32Characterization of U4 and U6 interactions with the 5' splice site using a S. cerevisiae in vitro trans-splicing systemThe 100-kda U5 snRNP protein (hPrp28p) contacts the 5' splice site through its ATPase siteA composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing.In vitro trans-splicing in Saccharomyces cerevisiaeIdentification of a human protein that recognizes the 3' splice site during the second step of pre-mRNA splicing.Suppressor U1 snRNAs in Drosophila.Reduction of target gene expression by a modified U1 snRNA.p54(nrb) associates with the 5' splice site within large transcription/splicing complexes.Splicing enhancement in the yeast rp51b intron.NTR1 is required for transcription elongation checkpoints at alternative exons in ArabidopsisFunctional interactions of Prp8 with both splice sites at the spliceosomal catalytic center.Branchpoint and polypyrimidine tract mutations mediating the loss and partial recovery of the Moloney murine sarcoma virus MuSVts110 thermosensitive splicing phenotype.Extraction of nuclei from sonchus yellow net rhabdovirus-infected plants yields a polymerase that synthesizes viral mRNAs and polyadenylated plus-strand leader RNAInhibitory activity of the equine infectious anemia virus major 5' splice site in the absence of RevThe Moloney murine sarcoma virus ts110 5' splice site signal contributes to the regulation of splicing efficiency and thermosensitivity.Characterization of the components and activity of Sonchus yellow net rhabdovirus polymerase.Evidence for the presence of a small U5-like RNA in active trans-spliceosomes of Trypanosoma brucei.Recognizing the 35th anniversary of the proposal that snRNPs are involved in splicing.Accumulation of a novel spliceosomal complex on pre-mRNAs containing branch site mutations.Hyperstable U1snRNA complementary to the K-ras transcripts induces cell death in pancreatic cancer cells.Co-transcriptional splicing of constitutive and alternative exonsProbing of the spliceosome with site-specifically derivatized 5' splice site RNA oligonucleotidesAntisense oligonucleotide binding to U5 snRNP induces a conformational change that exposes the conserved loop of U5 snRNA.The U1 snRNP base pairs with the 5' splice site within a penta-snRNP complex.Sequences upstream of the branch site are required to form helix II between U2 and U6 snRNA in a trans-splicing reaction.Genetics and biochemistry remain essential in the structural era of the spliceosome.Detection of a novel ATP-dependent cross-linked protein at the 5' splice site-U1 small nuclear RNA duplex by methylene blue-mediated photo-cross-linking.The pre-mRNA 5' cap determines whether U6 small nuclear RNA succeeds U1 small nuclear ribonucleoprotein particle at 5' splice sites.Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopyProximity of the U12 snRNA with both the 5' splice site and the branch point during early stages of spliceosome assemblyStructure of spliceosomal ribonucleoproteins.Functional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP.
P2860
Q24322003-96D08FEC-E9CC-48C6-91FB-D1EE51EA87D0Q24323409-97BB499A-3BCE-4EC9-A5D1-C0A931E5C31AQ24533375-53D48EC9-E8E3-4EB6-A775-A4B765A43C3EQ24539166-E7674E96-711B-49B8-921F-977CF81F8E07Q24539330-AFF96CA8-FA82-44AA-B4F2-862F33F30594Q24684791-E8CBB138-CB21-4CBF-8A50-C0AF41F0041DQ27939744-07BE1661-F9A8-4BBA-857A-7D340E43D6B2Q28278287-10BD4DD3-8972-42B2-82F6-AF5CE0161E4AQ28345350-316EE6D2-9C4C-43A8-8AD1-FABEE7A8BBD3Q28358525-1CCE4FF2-FDAE-449B-AC3A-2B4271F54280Q33285649-EC591FD1-6D06-4196-9D15-2B1A20E96583Q33701520-093577F3-407F-4F05-B481-7DA880BB0A4DQ33887127-FE748C40-B797-46D0-A697-4F3F5BA669CDQ33963665-5A480E43-A8B6-42F0-B9EE-56C7B6F944CCQ33967927-AC1A45C2-80E7-4D4C-8488-AE53F1541E7FQ34310192-B79B7B0C-4716-4D47-992B-E43CAED97F53Q34362457-5E06580D-EE56-486D-8D69-620B1A85193FQ35090680-54E3093D-8BBF-4C0D-B2F5-F28232E95B4AQ35203137-5B14F64A-B5E0-468C-839C-11AD79F5D5BAQ35852100-126AD579-3196-4909-8494-50FB71374874Q35853773-049BF19A-7504-4023-9BE5-163CE2BFFD18Q35861329-8AA564E0-264B-48B9-A17B-17678C8F1544Q35869074-85BE577B-24EC-48A2-8614-A0815AA1ED6AQ35879456-E54611A5-CAD9-44A5-A8BD-FE62453261A1Q35905891-332757BF-00B4-420A-B02B-751F13411296Q36156790-24D37724-B28A-4139-8051-BE919014CC6EQ36555468-1796D27C-5184-49E4-9EE0-AED8966FE6CAQ36646133-9BD64E73-0094-4892-BA06-F28B83E815CBQ37344492-AA73AD66-A220-47F0-AA8C-DC56CE6CF333Q38333283-E00F0EDA-E66F-493D-A40A-AB91C606A239Q38343294-2F0125AA-5F19-4DBE-A983-D31074C4624EQ38355126-E8184843-2135-4CC7-92D4-2AAD14B49CF4Q38678938-29847415-F1FA-4AF8-8679-DCBAF076ED3FQ39108397-FB046979-B225-463C-AEB4-7EDC71B3889AQ39576699-63E60662-2624-48AC-A6A0-AB8D4E1C259FQ39576977-7D336030-4253-468B-9AEC-2378F4335F0FQ41961878-10855124-1350-4677-813A-D2D9E39B5E0CQ42141598-2C63848D-49C7-434B-9C8B-7BA3E6F26172Q42413932-04219EC2-4DDF-49BD-BFEB-DF76DA747FFDQ43054928-C8EB29C1-5CA8-46FC-A09B-1C0251BC388E
P2860
Disruption of base pairing between the 5' splice site and the 5' end of U1 snRNA is required for spliceosome assembly.
description
1993 nî lūn-bûn
@nan
1993 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Disruption of base pairing bet ...... ired for spliceosome assembly.
@ast
Disruption of base pairing bet ...... ired for spliceosome assembly.
@en
Disruption of base pairing bet ...... ired for spliceosome assembly.
@nl
type
label
Disruption of base pairing bet ...... ired for spliceosome assembly.
@ast
Disruption of base pairing bet ...... ired for spliceosome assembly.
@en
Disruption of base pairing bet ...... ired for spliceosome assembly.
@nl
prefLabel
Disruption of base pairing bet ...... ired for spliceosome assembly.
@ast
Disruption of base pairing bet ...... ired for spliceosome assembly.
@en
Disruption of base pairing bet ...... ired for spliceosome assembly.
@nl
P2093
P1433
P1476
Disruption of base pairing bet ...... ired for spliceosome assembly.
@en
P2093
Konarska MM
Konforti BB
Koziolkiewicz MJ
P304
P356
10.1016/0092-8674(93)90531-T
P407
P577
1993-12-01T00:00:00Z