p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
about
Structure-Based Drug Discovery for Prion Disease Using a Novel Binding SimulationAutophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicityRegulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD.Differential expression of alpha-synuclein in hippocampal neurons.ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease.Type 2 diabetes as a protein misfolding disease.Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice.Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways.ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways.Lewy body-like α-synuclein aggregates resist degradation and impair macroautophagy.Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's DiseaseInclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosisToll-like receptor 2 is increased in neurons in Parkinson's disease brain and may contribute to alpha-synuclein pathology.Aberrant autophagy and parkinsonism: does correction rescue from disease progression?Protein recycling pathways in neurodegenerative diseases.Increased expression of p62/SQSTM1 in prion diseases and its association with pathogenic prion protein.Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses.Review: Spreading the word: precise animal models and validated methods are vital when evaluating prion-like behaviour of alpha-synuclein.Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain UbiquitinationDevelopment of the 5-HT2CR-Tango System Combined with an EGFP Reporter Gene.Overexpression of p62/SQSTM1 promotes the degradations of abnormally accumulated PrP mutants in cytoplasm and relieves the associated cytotoxicities via autophagy-lysosome-dependent way.The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease.Regulation of GPCR expression through an interaction with CCT7, a subunit of the CCT/TRiC complex.HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasisFrom autophagy to mitophagy: the roles of P62 in neurodegenerative diseases.Rab7 induces clearance of α-synuclein aggregates.
P2860
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P2860
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@ast
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@en
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@nl
type
label
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@ast
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@en
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@nl
prefLabel
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@ast
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@en
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@nl
P2093
P2860
P1433
P1476
p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions
@en
P2093
Harutsugu Tatebe
Katsutoshi Taguchi
Masaki Tanaka
Masanori Nakagawa
Takahiko Tokuda
Toshiki Mizuno
Yasuhisa Endo
Yoshihisa Watanabe
P2860
P304
P356
10.1371/JOURNAL.PONE.0052868
P407
P577
2012-12-31T00:00:00Z