Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse.
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An update on the role of intestinal cytochrome P450 enzymes in drug dispositionTRAM-34, a putatively selective blocker of intermediate-conductance, calcium-activated potassium channels, inhibits cytochrome P450 activityMice deficient in intestinal epithelium cytochrome P450 reductase are prone to acute toxin-induced mucosal damage.Intestinal epithelium-specific knockout of the cytochrome P450 reductase gene exacerbates dextran sulfate sodium-induced colitisNovel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.Role of intestinal cytochrome p450 enzymes in diclofenac-induced toxicity in the small intestine.NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.Regulation of intestinal cytochrome P450 expression by hepatic cytochrome P450: possible involvement of fibroblast growth factor 15 and impact on systemic drug exposure.In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences.Dealing with the complex drug-drug interactions: towards mechanistic models.Bioavailability enhancement of a BCS IV compound via an amorphous combination product containing ritonavir.Physiologically based pharmacokinetic modeling revealed minimal codeine intestinal metabolism in first-pass removal in rats.Effect of polymorphisms in CYP3A4, PPARA, NR1I2, NFKB1, ABCG2 and SLCO1B1 on the pharmacokinetics of lovastatin in healthy Chinese volunteers.Extrahepatic Drug-Metabolizing Enzymes and Their Significance
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P2860
Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Role of intestinal cytochrome ...... P450 reductase knockout mouse.
@ast
Role of intestinal cytochrome ...... P450 reductase knockout mouse.
@en
type
label
Role of intestinal cytochrome ...... P450 reductase knockout mouse.
@ast
Role of intestinal cytochrome ...... P450 reductase knockout mouse.
@en
prefLabel
Role of intestinal cytochrome ...... P450 reductase knockout mouse.
@ast
Role of intestinal cytochrome ...... P450 reductase knockout mouse.
@en
P2093
P2860
P356
P1476
Role of intestinal cytochrome ...... P450 reductase knockout mouse.
@en
P2093
Jaime D'Agostino
Qing-Yu Zhang
P2860
P304
P356
10.1124/DMD.110.037861
P577
2011-02-24T00:00:00Z