Heterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.

Heterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.

Item
http://www.wikidata.org/entity/Q35463734
A MutSβ-Dependent Contribution of MutSα to Repeat Expansions in Fragile X Premutation Mice?Ups and Downs: Mechanisms of Repeat Instability in the Fragile X-Related DisordersMutsβ generates both expansions and contractions in a mouse model of the Fragile X-associated disordersMultidrug Resistance-associated Protein-1 (MRP-1)-dependent Glutathione Disulfide (GSSG) Efflux as a Critical Survival Factor for Oxidant-enriched Tumorigenic Endothelial CellsOxidized dNTPs and the OGG1 and MUTYH DNA glycosylases combine to induce CAG/CTG repeat instability.Crosstalk between MSH2-MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair.CGG-repeat dynamics and FMR1 gene silencing in fragile X syndrome stem cells and stem cell-derived neurons.Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts.RNA biology of disease-associated microsatellite repeat expansions.R-loops: targets for nuclease cleavage and repeat instability.Timing of Expansion of Fragile X Premutation Alleles During Intergenerational Transmission in a Mouse Model of the Fragile X-Related Disorders
P2860

Heterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.

Item
http://www.wikidata.org/entity/Q35463734
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2015 nî lūn-bûn
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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2015 թվականի ապրիլին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Heterozygosity for a hypomorph ...... e Fragile X-related disorders.
@ast
Heterozygosity for a hypomorph ...... e Fragile X-related disorders.
@en
type
label
Heterozygosity for a hypomorph ...... e Fragile X-related disorders.
@ast
Heterozygosity for a hypomorph ...... e Fragile X-related disorders.
@en
prefLabel
Heterozygosity for a hypomorph ...... e Fragile X-related disorders.
@ast
Heterozygosity for a hypomorph ...... e Fragile X-related disorders.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Heterozygosity for a hypomorph ...... e Fragile X-related disorders.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PGEN.1005181
P433
P478
P577
P5875
P698
P932