Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD) - Wikidata - thesis-toulmin - TriplyDB

Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)

Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)

http://www.wikidata.org/entity/Q35545259

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Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1 Role of Drosophila Amyloid Precursor Protein in Memory Formation Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories.Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in Drosophila The structural biology of the amyloid precursor protein APP - a complex puzzle reveals its multi-domain architecture.Gene expression profiling in cells with enhanced gamma-secretase activity.APP processing induced by herpes simplex virus type 1 (HSV-1) yields several APP fragments in human and rat neuronal cells Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform.Knockdown of amyloid precursor protein in zebrafish causes defects in motor axon outgrowth.Tip60 HAT activity mediates APP induced lethality and apoptotic cell death in the CNS of a Drosophila Alzheimer's disease model.Epigenetic control of learning and memory in Drosophila by Tip60 HAT action.Dysregulation of Ca2+ signaling in astrocytes from mice lacking amyloid precursor protein.All in the Family: How the APPs Regulate Neurogenesis Tip60 HAT Action Mediates Environmental Enrichment Induced Cognitive Restoration.Amyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles.The keystone of Alzheimer pathogenesis might be sought in Aβ physiology Tip off the HAT- Epigenetic control of learning and memory by Drosophila Tip60 The amyloid precursor protein (APP) family members are key players in S-adenosylmethionine formation by MAT2A and modify BACE1 and PSEN1 gene expression-relevance for Alzheimer's disease.Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role A TAG on to the neurogenic functions of APP ACE inhibition with captopril retards the development of signs of neurodegeneration in an animal model of Alzheimer's disease Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain.Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's Disease Nitric Oxide: Exploring the Contextual Link with Alzheimer's Disease Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain.Pharmacological targeting of the β-amyloid precursor protein intracellular domain.Biology and pathophysiology of the amyloid precursor protein.Analysis of amyloid precursor protein function in Drosophila melanogaster.The physiology of the β-amyloid precursor protein intracellular domain AICD.The role of APP proteolytic processing in lipid metabolism.The role of S100a9 in the pathogenesis of Alzheimer's disease: the therapeutic effects of S100a9 knockdown or knockout.Physiological functions of APP family proteins.From synaptic spines to nuclear signaling: nuclear and synaptic actions of the amyloid precursor protein.Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities.Redox proteomics gives insights into the role of oxidative stress in alkaptonuria.

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Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)

http://www.wikidata.org/entity/Q35545259

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2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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Modulation of gene expression ...... in intracellular domain (AICD)

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Modulation of gene expression ...... in intracellular domain (AICD)

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Modulation of gene expression ...... in intracellular domain (AICD)

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Molecular Biology of the Cell

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Modulation of gene expression ...... in intracellular domain (AICD)

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Anca L Tirniceriu

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Caoimhin G Concannon

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Ciara M Walsh

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Donat Kögel

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Florian Tribl

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Rupert Egensperger

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Thorsten Müller

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P2860

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo

Pathways towards and away from Alzheimer's disease

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Neuropathological stageing of Alzheimer-related changes

Notch signaling: cell fate control and signal integration in development

The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton.

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

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10.1091/MBC.E06-04-0283

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18

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