Notch signaling: cell fate control and signal integration in development
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Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cellsNotch signaling and ghost cell fate in the calcifying cystic odontogenic tumorMain roads to melanomaHematopoietic stem cell development, niches, and signaling pathwaysSKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC functionDll4, a novel Notch ligand expressed in arterial endotheliumCyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3Jagged2 induces cell cycling in confluent fibroblasts susceptible to density-dependent inhibition of cell divisionThe notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cellsA human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promotersSoluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotypeHERP, a novel heterodimer partner of HES/E(spl) in Notch signalingModification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferaseMembers of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interactionRole of Deltex-1 as a transcriptional regulator downstream of the Notch receptorDifferential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiationThe p53 family member genes are involved in the Notch signal pathwayIntegrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cellsConserved signal peptide of Notch3 inhibits interaction with proteasomeNotch1 augments NF-kappaB activity by facilitating its nuclear retentionThe notch regulator MAML1 interacts with p53 and functions as a coactivatorNotch inhibits apoptosis by direct interference with XIAP ubiquitination and degradationOverexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterationsThe nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathwayNotch signaling is essential for ventricular chamber developmentSlc35c2 promotes Notch1 fucosylation and is required for optimal Notch signaling in mammalian cellsSegmental expression of Notch and Hairy genes in nephrogenesisTranscriptional regulation by FOXP1, FOXP2, and FOXP4 dimerizationJagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgammaMT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell developmentIncreased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanismThe Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesisMutations in NOTCH1 cause aortic valve diseaseRITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.Botch promotes neurogenesis by antagonizing NotchJagged1 (JAG1) mutations in patients with tetralogy of Fallot or pulmonic stenosisIdentification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotypeThe prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
P2860
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P2860
Notch signaling: cell fate control and signal integration in development
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Notch signaling: cell fate control and signal integration in development
@ast
Notch signaling: cell fate control and signal integration in development
@en
Notch signaling: cell fate control and signal integration in development
@nl
type
label
Notch signaling: cell fate control and signal integration in development
@ast
Notch signaling: cell fate control and signal integration in development
@en
Notch signaling: cell fate control and signal integration in development
@nl
prefLabel
Notch signaling: cell fate control and signal integration in development
@ast
Notch signaling: cell fate control and signal integration in development
@en
Notch signaling: cell fate control and signal integration in development
@nl
P2093
P3181
P1433
P1476
Notch signaling: cell fate control and signal integration in development
@en
P2093
S Artavanis-Tsakonas
P3181
P356
10.1126/SCIENCE.284.5415.770
P407
P577
1999-04-30T00:00:00Z