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Modulation of osteoclast differentiation and bone resorption by Rho GTPasesRegulation of osteoclasts by membrane-derived lipid mediatorsOxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasisc-Src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton.Paxillin contracts the osteoclast cytoskeletonZap70 inhibits Syk-mediated osteoclast function.Vinculin regulates osteoclast functionRegulation of Embryonic and Postnatal Development by the CSF-1 Receptor.Importance of RhoGTPases in formation, characteristics, and functions of invadosomes.Podosome organization drives osteoclast-mediated bone resorption.Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangementsAbsence of Dap12 and the αvβ3 integrin causes severe osteopetrosis.The Roles of Small GTPases in Osteoclast BiologyOsteoclasts: New InsightsThe collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption.TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.Talin1 and Rap1 are critical for osteoclast function.Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo.Membrane trafficking in osteoblasts and osteoclasts: new avenues for understanding and treating skeletal diseasesOsteoclasts-Key Players in Skeletal Health and Disease.Therapeutic potentials of naringin on polymethylmethacrylate induced osteoclastogenesis and osteolysis, in vitro and in vivo assessments.Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts.Role and mechanism of action of leucine-rich repeat kinase 1 in bone.Repositioning Potential of PAK4 to Osteoclastic Bone Resorption.An Osteoclastic Transmembrane Protein-Tyrosine Phosphatase Enhances Osteoclast Activity in Part by Dephosphorylating EphA4 in Osteoclasts.Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation.Multinucleated Giant Cells Are Specialized for Complement-Mediated Phagocytosis and Large Target Destruction.Involvement of geranylgeranylation of Rho and Rac GTPases in adipogenic and RANKL expression, which was inhibited by simvastatin.The HIV co-receptor CCR5 regulates osteoclast function.TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42.p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption.An Antibody to Notch2 Reverses the Osteopenic Phenotype of Hajdu-Cheney Mutant Male Mice.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Rac deletion in osteoclasts causes severe osteopetrosis
@ast
Rac deletion in osteoclasts causes severe osteopetrosis
@en
type
label
Rac deletion in osteoclasts causes severe osteopetrosis
@ast
Rac deletion in osteoclasts causes severe osteopetrosis
@en
prefLabel
Rac deletion in osteoclasts causes severe osteopetrosis
@ast
Rac deletion in osteoclasts causes severe osteopetrosis
@en
P2093
P2860
P356
P1476
Rac deletion in osteoclasts causes severe osteopetrosis
@en
P2093
David A Williams
F Patrick Ross
Matti Korhonen
Monica Croke
P2860
P304
P356
10.1242/JCS.086280
P407
P577
2011-11-23T00:00:00Z