A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
about
Stabilization and Degradation Mechanisms of Cytoplasmic Ataxin-1.Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes.TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.Chaperones in Polyglutamine Aggregation: Beyond the Q-Stretch.Structural, morphological, and functional diversity of amyloid oligomers.Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation.Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.Motor neuron degeneration correlates with respiratory dysfunction in SCA1.The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer.Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease
P2860
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P2860
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
@ast
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
@en
type
label
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
@ast
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
@en
prefLabel
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
@ast
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
@en
P2093
P2860
P50
P356
P1433
P1476
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1
@en
P2093
Alexandra Litvinchuk
Cristian A Lasagna-Reeves
Jeehye Park
Marcos J Guerrero-Muñoz
Paymaan Jafar-Nejad
Rakez Kayed
Ronald Richman
Urmi Sengupta
P2860
P356
10.7554/ELIFE.07558
P407
P577
2015-05-19T00:00:00Z