Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor
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The role of the ubiquitin proteasome system in cerebellar development and medulloblastomaBortezomib treatment produces nocifensive behavior and changes in the expression of TRPV1, CGRP, and substance P in the rat DRG, spinal cord, and sciatic nerve.Down-regulation of 11β-hydroxysteroid dehydrogenase type 2 by bortezomib sensitizes Jurkat leukemia T cells against glucocorticoid-induced apoptosis.Morphoproteomics identifies constitutive activation of the mTORC2/Akt and NF-κB pathways and expressions of IGF-1R, Sirt1, COX-2, and FASN in peripheral T-cell lymphomas: pathogenetic implications and therapeutic options.Reversal of bortezomib resistance in myelodysplastic syndrome cells by MAPK inhibitors.Annona muricata leaves induced apoptosis in A549 cells through mitochondrial-mediated pathway and involvement of NF-κB.Simultaneous suppression of the MAP kinase and NF-κB pathways provides a robust therapeutic potential for thyroid cancerCombined bortezomib-based chemotherapy and p53 gene therapy using hollow mesoporous silica nanospheres for p53 mutant non-small cell lung cancer treatment.Regulation of dimethyl-fumarate toxicity by proteasome inhibitorsThe rationale for targeted therapies in medulloblastoma.Mitotic catastrophe and cell cycle arrest are alternative cell death pathways executed by bortezomib in rituximab resistant B-cell lymphoma cellsCombination Treatment with Sublethal Ionizing Radiation and the Proteasome Inhibitor, Bortezomib, Enhances Death-Receptor Mediated Apoptosis and Anti-Tumor Immune Attack.Protective role of humanin on bortezomib-induced bone growth impairment in anticancer treatment.Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line.Proteasome Inhibitor YSY01A Abrogates Constitutive STAT3 Signaling via Down-regulation of Gp130 and JAK2 in Human A549 Lung Cancer Cells.Annonaceae: Breaking the Wall of Inflammation.Proteasome inhibitors against amelanotic melanoma.The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.Hinokitiol Inhibits Migration of A549 Lung Cancer Cells via Suppression of MMPs and Induction of Antioxidant Enzymes and Apoptosis.
P2860
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P2860
Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor
description
2012 nî lūn-bûn
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2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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2012年论文
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2012年论文
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name
Bortezomib induces apoptosis a ...... nergizes with an ERK inhibitor
@ast
Bortezomib induces apoptosis a ...... nergizes with an ERK inhibitor
@en
type
label
Bortezomib induces apoptosis a ...... nergizes with an ERK inhibitor
@ast
Bortezomib induces apoptosis a ...... nergizes with an ERK inhibitor
@en
prefLabel
Bortezomib induces apoptosis a ...... nergizes with an ERK inhibitor
@ast
Bortezomib induces apoptosis a ...... nergizes with an ERK inhibitor
@en
P2093
P2860
P356
P1476
Bortezomib induces apoptosis a ...... nergizes with an ERK inhibitor
@en
P2093
Anna Scuto
M L Richard Yip
Michael Hedvat
Ralf Buettner
Richard Jove
Shirley Chang
Timothy Van Meter
Veronica Jove
P2860
P304
P356
10.4161/CBT.19239
P577
2012-04-01T00:00:00Z