Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells
about
Cancer prevention with promising natural products: mechanisms of action and molecular targetsSarcopenia: pharmacology of today and tomorrowIcariside II induces apoptosis in U937 acute myeloid leukemia cells: role of inactivation of STAT3-related signalingJSI-124 suppresses invasion and angiogenesis of glioblastoma cells in vitroUrsolic acid-mediated apoptosis of K562 cells involves Stat5/Akt pathway inhibition through the induction of Gfi-1Therapeutic modulators of STAT signalling for human diseasesKinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6.Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3.YLT192, a novel, orally active bioavailable inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy in preclinical modelsUrsolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathwaysAction of RORs and their ligands in (patho)physiology.REV-ERB and ROR nuclear receptors as drug targets.Ursolic acid induces cell cycle arrest and apoptosis of gallbladder carcinoma cells.Characterizing Vaccinium berry Standard Reference Materials by GC-MS using NIST spectral libraries.Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNKPropolis augments apoptosis induced by butyrate via targeting cell survival pathways.Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t proteinEvolution in medicinal chemistry of ursolic acid derivatives as anticancer agentsSignal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approachInduction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory network.Age-associated chronic diseases require age-old medicine: role of chronic inflammation.Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitorUrsolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathwayUrsolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells.Ursolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells.Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs.A phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors.Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells.Targeting proliferation and survival pathways in head and neck cancer for therapeutic benefitCancer cell signaling pathways targeted by spice-derived nutraceuticals.Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabineStructural and bioactive studies of terpenes and cyclopeptides from the Genus RubiaUrsolic acid inhibits the growth of human pancreatic cancer and enhances the antitumor potential of gemcitabine in an orthotopic mouse model through suppression of the inflammatory microenvironmentUrsolic acid attenuates temozolomide resistance in glioblastoma cells by downregulating O(6)-methylguanine-DNA methyltransferase (MGMT) expressionUrsolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1α.Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.
P2860
Q27006530-7B1A066B-D9F9-4E91-80C8-B1A747D23AF9Q27687696-4548460F-0D0E-4D78-AFEE-C3F3FBF04F69Q28482163-06836971-7C1F-4430-85C8-24FCDB9DD5A6Q28544728-11DA8878-4575-420B-9402-1F9195FB0628Q28830045-086F0D17-7F23-4E1B-9252-AC8CAC907A06Q33684732-B8B61195-4601-4161-B39D-02E3512DE148Q33697369-FEACA717-EC2A-4B06-BC38-51884444279DQ33780701-B70F6C70-AEC4-4269-9644-8B68DC388116Q33945427-4C952FEF-6324-4914-9CD2-F3CF64407346Q34030791-51F95AA6-DDFB-4037-8412-5E83FB33F772Q34199851-B81A4606-D67C-4786-8296-5BA12004861EQ34287702-2B6F891C-4672-4C35-B988-70A000741B59Q34407313-35A12F52-3A97-4D7E-8796-697AD154EEE4Q34474342-97C44113-82ED-4682-89EE-7449AF3AEC34Q34537438-43C2B348-0F6A-47B3-9E70-7F5470A18B15Q34568521-DC34CF3D-EB19-4ABE-89F0-65A18844D18EQ34984246-D09F8671-AE8D-4442-B503-268D54FE9644Q35067655-63FCE8AB-CC24-4351-B079-E8F09465086DQ35108020-09C39386-2261-41F7-A255-1B4CF550C930Q35120899-FEF30572-FC08-429E-9B2B-CD20F4B3E218Q35155622-A289BCBA-4578-4BC5-8CAD-F2386A128F23Q35206870-2F04E1A0-6C05-4BA8-9DBC-5C70E772025DQ35760870-572EDE80-069F-4131-8B38-59E649DF6D21Q35863370-B29DAE7B-9F3E-4DEB-A8C8-237C3F1764FBQ35923150-EC864D05-A4B0-4E9A-9E6A-A9703D3FCE6FQ35925413-F9B373F9-BB31-4834-944E-821470175CC4Q36025363-67B6E0BE-EB6A-42FA-9F14-E8A55061C699Q36089852-04D364D9-570C-414F-9FC6-E9AED4B768C6Q36100030-2B49A065-5B43-4572-9048-FA46472E8A09Q36494764-3BC75511-70E7-4062-A564-828B09CD4998Q36520764-D4A90A3C-C2C6-44F0-826D-AB0D4C35D4FCQ36556245-A9E465A9-742F-4B9C-8500-EFCBE6924A1EQ36713669-70ED68B9-0349-4845-B424-46B935A1670BQ36819371-26753E8F-E544-44BE-BD4E-C9AFBC784C14Q36916312-543DF656-3E04-4FDA-827F-44556C819884Q36972564-CB07135A-8EC7-4ADE-9C5C-7F54CE268A86Q37022420-D68DADB9-9D8D-4DF9-B1CD-40719EA8E030Q37144157-17F74DC4-1BAA-46FC-84C1-2E951CE45C47Q37247157-4D180AF1-DCA6-4A14-ABF6-B766224B37D3Q37341171-E8C5F5DA-C0C6-4897-BA5C-5C4F17B1B36F
P2860
Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@ast
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@en
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@nl
type
label
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@ast
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@en
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@nl
prefLabel
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@ast
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@en
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@nl
P2093
P3181
P1476
Ursolic acid inhibits STAT3 ac ...... f human multiple myeloma cells
@en
P2093
Arup Chakraborty
Asha S Nair
Ashutosh K Pathak
Bharat B Aggarwal
Humam Kadara
Kwang Seok Ahn
Manisha Bhutani
Sushovan Guha
P304
P3181
P356
10.1158/1541-7786.MCR-06-0348
P407
P50
P577
2007-09-01T00:00:00Z