The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. - Wikidata - thesis-toulmin - TriplyDB

The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

http://www.wikidata.org/entity/Q36257261

about

A missense mutation in PMEL17 is associated with the Silver coat color in the horse The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis Retrotransposon insertion in SILV is responsible for merle patterning of the domestic dog.Melanosomes--dark organelles enlighten endosomal membrane transport Bird Integumentary Melanins: Biosynthesis, Forms, Function and Evolution Melanoma-associated leukoderma - immunology in black and white?Circulating serologic and molecular biomarkers in malignant melanoma Emerging roles of extracellular vesicles in the nervous system PMEL Amyloid Fibril Formation: The Bright Steps of Pigmentation Update on the regulation of mammalian melanocyte function and skin pigmentation Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation Identification of genes associated with shell color in the black-lipped pearl oyster, Pinctada margaritifera Signatures of positive selection in East African Shorthorn Zebu: A genome-wide single nucleotide polymorphism analysis Evolution of pigment synthesis pathways by gene and genome duplication in fish MHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes.Electron tomography of early melanosomes: implications for melanogenesis and the generation of fibrillar amyloid sheets.Molecular and developmental contributions to divergent pigment patterns in marine and freshwater sticklebacks Equine multiple congenital ocular anomalies and silver coat colour result from the pleiotropic effects of mutant PMEL.Genetic effects on coat colour in cattle: dilution of eumelanin and phaeomelanin pigments in an F2-Backcross Charolais x Holstein population.Multiple splice variants within the bovine silver homologue (SILV) gene affecting coat color in cattle indicate a function additional to fibril formation in melanophores.The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding.Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.Rab7 is a critical mediator in vesicular transport of tyrosinase-related protein 1 in melanocytes.Endoplasmic reticulum export, subcellular distribution, and fibril formation by Pmel17 require an intact N-terminal domain junction.Diagnostic and prognostic biomarkers in melanoma.Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in the SLC45A2 gene.Two SNPs in the SILV gene are associated with silver coat colour in ponies.Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic Interaction of MC1R and PMEL alleles on solid coat colors in Highland cattle.Teaching an old dog new tricks: SINEs of canine genomic diversity.Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17.Single-nucleotide polymorphisms in pigment genes and nonmelanoma skin cancer predisposition: a systematic review.Spectral analysis by XANES reveals that GPNMB influences the chemical composition of intact melanosomes.Alzheimer's disease beta-amyloid peptides are released in association with exosomes.Repeat domains of melanosome matrix protein Pmel17 orthologs form amyloid fibrils at the acidic melanosomal pH.Lysophospholipid-containing membranes modulate the fibril formation of the repeat domain of a human functional amyloid, pmel17.Proprotein convertases process Pmel17 during secretion.WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition.

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P2860

The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

http://www.wikidata.org/entity/Q36257261

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

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The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

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The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

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The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

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The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

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J.1600-0749.2005.00269.X

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Pigment Cell & Melanoma Research

P1476

The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.

@en

P2093

Alexander C Theos

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Graça Raposo

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Michael S Marks

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Steven T Truschel

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P2860

Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia

Pmel17 initiates premelanosome morphogenesis within multivesicular bodies

MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes

The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteins

nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts

Cloning and expression of the gene for the melanoma-associated ME20 antigen

Epitope mapping of the melanosomal matrix protein gp100 (PMEL17): rapid processing in the endoplasmic reticulum and glycosylation in the early Golgi compartment

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3.

The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease.

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322-336

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10.1111/J.1600-0749.2005.00269.X

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5

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18

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16162173

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2788625

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