Granuphilin molecularly docks insulin granules to the fusion machinery.
about
Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapseExophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domainβ-Cell MicroRNAs: Small but PowerfulMultiple roles for the actin cytoskeleton during regulated exocytosisMicroRNAs in insulin resistance and obesitySignaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cellsGene expression profiling of a mouse model of pancreatic islet dysmorphogenesisResident CAPS on dense-core vesicles docks and primes vesicles for fusionA novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cellsGranuphilin exclusively mediates functional granule docking to the plasma membrane.MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cellsNeurexin-1α contributes to insulin-containing secretory granule dockingDistinct actions of Rab3 and Rab27 GTPases on late stages of exocytosis of insulin.Regulation of cellular communication by signaling microdomains in the blood vessel wall.Exophilin8 transiently clusters insulin granules at the actin-rich cell cortex prior to exocytosis.The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane.Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodiesNkx6.1 is essential for maintaining the functional state of pancreatic beta cells.Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa.Mapping dynamic protein interactions to insulin secretory granule behavior with TIRF-FRET.Gene networks modified by sulphonylureas in beta cells: a pathway-based analysis of insulin secretion and cell death.ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis.Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice.Minireview: microRNA function in pancreatic β cells.Altered pancreatic islet function and morphology in mice lacking the Beta-cell surface protein neuroligin-2.Expression of Secretogranin III in Chicken Endocrine Cells: Its Relevance to the Secretory Granule Properties of Peptide Prohormone Processing and Bioactive Amine Content.Survey of Red Fluorescence Proteins as Markers for Secretory Granule ExocytosisModular genetic control of sexually dimorphic behaviors.Evolving insights regarding mechanisms for the inhibition of insulin release by norepinephrine and heterotrimeric G proteins.In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule traffickingChanges in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD miceOn the immense variety and complexity of circumstances conditioning pancreatic β-cell apoptosis in type 1 diabetesRab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane.PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport.Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral AssessmentsSynaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cellsInsulin vesicle release: walk, kiss, pause ... then run.Role of Rab27 in synaptic transmission at the squid giant synapseSecretory vesicle docking to the plasma membrane: molecular mechanism and functional significance.
P2860
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P2860
Granuphilin molecularly docks insulin granules to the fusion machinery.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Granuphilin molecularly docks insulin granules to the fusion machinery.
@ast
Granuphilin molecularly docks insulin granules to the fusion machinery.
@en
type
label
Granuphilin molecularly docks insulin granules to the fusion machinery.
@ast
Granuphilin molecularly docks insulin granules to the fusion machinery.
@en
prefLabel
Granuphilin molecularly docks insulin granules to the fusion machinery.
@ast
Granuphilin molecularly docks insulin granules to the fusion machinery.
@en
P2093
P2860
P356
P1476
Granuphilin molecularly docks insulin granules to the fusion machinery
@en
P2093
Hiroshi Gomi
Kazuo Kasai
Shin Mizutani
Tetsuro Izumi
P2860
P304
P356
10.1083/JCB.200505179
P407
P50
P577
2005-10-01T00:00:00Z