Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn.
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Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophilsComparative Anatomy of Phagocytic and Immunological SynapsesDifferential Enhancement of Dengue Virus Immune Complex Infectivity Mediated by Signaling-Competent and Signaling-Incompetent Human Fc RIA (CD64) or Fc RIIA (CD32)Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophagesRestricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosisThe SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif.Neutrophil cell surface receptors and their intracellular signal transduction pathways.The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.Macrophage Polarization Modulates FcγR- and CD13-Mediated Phagocytosis and Reactive Oxygen Species Production, Independently of Receptor Membrane Expression.Quantitative analysis of membrane remodeling at the phagocytic cup.Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway.Anti-HPA-1a-mediated platelet phagocytosis by monocytes in vitro and its inhibition by Fc gamma receptor (FcgammaR) reactive reagents.Alveolar epithelial type II cells activate alveolar macrophages and mitigate P. Aeruginosa infection.Use of a Monocyte Monolayer Assay to Evaluate Fcγ Receptor-mediated Phagocytosis.The Haemophilus ducreyi LspA1 protein inhibits phagocytosis by using a new mechanism involving activation of C-terminal Src kinase.Haemophilus ducreyi targets Src family protein tyrosine kinases to inhibit phagocytic signaling.The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitmentGenetic deficiency of Syk protects mice from autoantibody-induced arthritis.Critical role of galectin-3 in phagocytosis by macrophages.Recognition and phagocytosis of apoptotic T cells by resident murine tissue macrophages require multiple signal transduction events.Rate and extent of phagocytosis in macrophages lacking vamp3.Immunoglobulin G signaling activates lysosome/phagosome docking.Targeting Syk as a treatment for allergic and autoimmune disorders.Src family kinases are important negative regulators of G-CSF-dependent granulopoiesisLyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related PhagocytosisFc receptor targeting in the treatment of allergy, autoimmune diseases and cancer.Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritisThe role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells.LynA regulates an inflammation-sensitive signaling checkpoint in macrophages.Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosisThe role of Src kinase in macrophage-mediated inflammatory responses.Src protein tyrosine kinase family and acute inflammatory responses.Signal transduction pathways that contribute to myeloid differentiation.Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.Src family kinases and the MEK/ERK pathway in the regulation of myeloid differentiation and myeloid leukemogenesisReceptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells.The diverse functions of Src family kinases in macrophages.The absence of Hck, Fgr, and Lyn tyrosine kinases augments lung innate immune responses to Pneumocystis murina.Multiple roles of Lyn kinase in myeloid cell signaling and function.
P2860
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P2860
Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
Fcgamma receptor-mediated phag ...... ine kinases Hck, Fgr, and Lyn.
@ast
Fcgamma receptor-mediated phag ...... ine kinases Hck, Fgr, and Lyn.
@en
type
label
Fcgamma receptor-mediated phag ...... ine kinases Hck, Fgr, and Lyn.
@ast
Fcgamma receptor-mediated phag ...... ine kinases Hck, Fgr, and Lyn.
@en
prefLabel
Fcgamma receptor-mediated phag ...... ine kinases Hck, Fgr, and Lyn.
@ast
Fcgamma receptor-mediated phag ...... ine kinases Hck, Fgr, and Lyn.
@en
P2093
P2860
P356
P1476
Fcgamma receptor-mediated phag ...... ine kinases Hck, Fgr, and Lyn.
@en
P2093
A L DeFranco
C A Lowell
C J Fitzer-Attas
M T Crowley
P2860
P304
P356
10.1084/JEM.191.4.669
P407
P577
2000-02-01T00:00:00Z