Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration.
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A Review of Animal Models of Intervertebral Disc Degeneration: Pathophysiology, Regeneration, and Translation to the ClinicMolecular mechanisms of biological aging in intervertebral discsDiversity of intervertebral disc cells: phenotype and functionThe germline/soma dichotomy: implications for aging and degenerative diseaseInvestigation of the relationship between chromobox homolog 8 and nucleus pulposus cells degeneration in rat intervertebral discGlobal identification of genes related to nutrient deficiency in intervertebral disc cells in an experimental nutrient deprivation modelProtective role of 17β-estradiol on tumor necrosis factor-α-induced apoptosis in human nucleus pulposus cellsSenescent vs. non-senescent cells in the human annulus in vivo: cell harvest with laser capture microdissection and gene expression studies with microarray analysis.The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degenerationCharacterization of the age-dependent intervertebral disc changes in rabbit by correlation between MRI, histology and gene expression.Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining.Novel immortal human cell lines reveal subpopulations in the nucleus pulposus.Human umbilical cord blood-derived mesenchymal stem cells in the cultured rabbit intervertebral disc: a novel cell source for disc repairEx vivo observation of human nucleus pulposus chondrocytes isolated from degenerated intervertebral discsKnockdown Epithelial Membrane Protein 1 Suppresses Human Degenerative Intervertebral Disc-Derived Nucleus Pulposus Cell Proliferation.MR monitoring of minimally invasive delivery of mesenchymal stem cells into the porcine intervertebral disc.Sox9 gene transfer enhanced regenerative effect of bone marrow mesenchymal stem cells on the degenerated intervertebral disc in a rabbit model.The role of microRNAs in cellular senescence and age-related conditions of cartilage and bone.Physiological loading can restore the proteoglycan content in a model of early IVD degeneration.Low back pain associated with lumbar disc herniation: role of moderately degenerative disc and annulus fibrous tears.Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells.Porcine intervertebral disc repair using allogeneic juvenile articular chondrocytes or mesenchymal stem cellsCaveolin-1, cellular senescence and age-related diseases.Regenerative potential of TGFβ3 + Dex and notochordal cell conditioned media on degenerated human intervertebral disc cells.Relationship between Initial Telomere Length, Initial Telomerase Activity, Age, and Replicative Capacity of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs: What Is a Predictor of Replicative Potential?Spine degeneration in a murine model of chronic human tobacco smokersThe distribution pattern of critically short telomeres in human osteoarthritic knees.Combined activation of the energy and cellular-defense pathways may explain the potent anti-senescence activity of methylene blue.Experimental observation of human bone marrow mesenchymal stem cell transplantation into rabbit intervertebral discs.Accelerated aging of intervertebral discs in a mouse model of progeria.Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile.Combined effect of 17β-estradiol and resveratrol against apoptosis induced by interleukin-1β in rat nucleus pulposus cells via PI3K/Akt/caspase-3 pathway.Degenerative grade affects the responses of human nucleus pulposus cells to link-N, CTGF, and TGFβ3.Genotoxic stress accelerates age-associated degenerative changes in intervertebral discsSIRT1 alleviates senescence of degenerative human intervertebral disc cartilage endo-plate cells via the p53/p21 pathway.Increased caveolin-1 in intervertebral disc degeneration facilitates repairEnhancement of intervertebral disc cell senescence by WNT/β-catenin signaling-induced matrix metalloproteinase expression.17β-Estradiol Protects Rat Annulus Fibrosus Cells Against Apoptosis via α1 Integrin-Mediated Adhesion to Type I Collagen: An In-vitro Study.Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration.Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapiesfor intervertebral disc degeneration.
P2860
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P2860
Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Accelerated cellular senescenc ...... ervertebral disc degeneration.
@ast
Accelerated cellular senescenc ...... ervertebral disc degeneration.
@en
type
label
Accelerated cellular senescenc ...... ervertebral disc degeneration.
@ast
Accelerated cellular senescenc ...... ervertebral disc degeneration.
@en
prefLabel
Accelerated cellular senescenc ...... ervertebral disc degeneration.
@ast
Accelerated cellular senescenc ...... ervertebral disc degeneration.
@en
P2093
P2860
P356
P1476
Accelerated cellular senescenc ...... ervertebral disc degeneration.
@en
P2093
Anthony John Freemont
Christine Lyn Le Maitre
Judith Alison Hoyland
P2860
P2888
P356
10.1186/AR2198
P577
2007-01-01T00:00:00Z
P5875
P6179
1015441467