Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases.
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Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoformsCloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1.The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5qIdentification and characterization of the human Set1B histone H3-Lys4 methyltransferase complexLeucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemiaTwo distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivatorsMammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeresDnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcriptionCpG binding protein is crucial for early embryonic developmentMechanism of transcriptional regulation by methyl-CpG binding protein MBD1Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 geneMeis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 miceThe structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domainMLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell linesThe synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10Identification of a conserved family of Meis1-related homeobox genesIdentification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissuesIdentification of a sequence-specific single-stranded DNA binding protein that suppresses transcription of the mouse myelin basic protein geneFunctional specificity of CpG DNA-binding CXXC domains in mixed lineage leukemia.CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin.Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein.The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.Identification and characterization of the DNA binding domain of CpG-binding protein.Chromatin modification and diseaseLeukemias related to treatment with DNA topoisomerase II inhibitors.Involvement of the ALL-1 gene in a solid tumor.CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex.MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers.Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin.ALL-1 partial duplication in acute leukemia.C/EBPbeta suppression by interruption of CUGBP1 resulting from a complex rearrangement of MLL.The common cytokine receptor gamma chain controls survival of gamma/delta T cells.MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).Mechanisms of transcription factor deregulation in lymphoid cell transformation.The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.The Drosophila trithorax protein binds to specific chromosomal sites and is co-localized with Polycomb at many sites.Novel DNA binding domain-based assays for detection of methylated and nonmethylated DNA.
P2860
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P2860
Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Analysis of the murine All-1 g ...... d with DNA methyltransferases.
@ast
Analysis of the murine All-1 g ...... d with DNA methyltransferases.
@en
type
label
Analysis of the murine All-1 g ...... d with DNA methyltransferases.
@ast
Analysis of the murine All-1 g ...... d with DNA methyltransferases.
@en
prefLabel
Analysis of the murine All-1 g ...... d with DNA methyltransferases.
@ast
Analysis of the murine All-1 g ...... d with DNA methyltransferases.
@en
P2093
P2860
P356
P1476
Analysis of the murine All-1 g ...... d with DNA methyltransferases.
@en
P2093
A M Buchberg
D Chatterjee
K K Nelson
L D Siracusa
T Nakamura
P2860
P304
P356
10.1073/PNAS.90.13.6350
P407
P577
1993-07-01T00:00:00Z